3-(Dimethylamino)propionitrile 3-(二甲基氨基)丙腈

CAS 1738-25-6 MFCD00001957

化学结构图

1738-25-6
SMILES: CN(C)CCC#N

化学属性

Mol. FormulaC5H10N2
Mol. Weight98
Density0.87
Refractive index1.4260 to 1.4270
Boiling Point171
Melting Point-43
Flash Point64°C(lit.)
Solubility0.5 G/L (20 ºC)

别名和识别编码

Chemical Name3-(Dimethylamino)propionitrile
Synonym 二甲氨基丙腈 3-(DIMETHYLAMINO)PROPIONITRILE 2-二甲氨基乙基氰 2-Dimthylaminoethyl cyanide DMAPN 3-(二甲基氨基)丙腈 β-N-dimethy N,N-dimethyl-β-alanine nitrile propionitrile, 3-(dimethylamino)- 3-(dimethylamino)propionitrile nitrile of 3-dimethylaminopropionic acid 3-dimethylaminopropannitril {Chemi 3-(Dimethylamino)-propionitrile 3-(N,N-Dimethylamino)propionitrile β-(Dimethylamino)propionitrile 2-(二甲胺基)乙基氰 beta-(N-Dimethylamino)propionitrile 3-(Dimethylamino)-propionsäurenitril 3-(dimethylamino)-propionitril N,N-(Dimethylamino)-3-propionitrile 2-DIMETHYLAMINOETHYL CYANIDE Β-二甲氨基丙腈 beta-n-dimethylaminopropionitrile 3-二甲氨基丙腈 3-(Dimethyl 3-(DIMETHYLAMINO)PROPIONONITRILE 3-(dimethylamino)-Propanenitrile 3-(dimethylamino)propanenitrile Propi 3-(dimethylamino)-propanenitrile beta-Dimethylaminopropionitrile 3-(dimethylamino)-propanenitril 3-(Di 3-Dimethylaminopropionsäurenitril N,N-dimeth β-二甲氨基丙腈 3-Dimethylaminopropionitrile β-(N-Dimethylamino)propionitrile n,n-dimethylamino-3-propionitrile Propanenitrile, 3-(dimethylamino)- 3-(Dimethylamino)propionitrile N,N-Dimethyl-2-cyanoethylamine 3-Dimethylaminopropannitril 2-(二甲氨基)乙基氰 3-Dimethylaminopropanonitrile β-Dimethylaminopropionitrile 3-(N,N
CAS Number1738-25-6
EC Number217-090-4
Beilstein Registry Number773779
MDL NumberMFCD00001957
PubChem Substance ID87567303
Reaxys-RN773779
Chemical Name Translation3-(二甲基氨基)丙腈
Wiswesser Line NotationNC2N1&1
LabNetwork Molecule IDLN00192900
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分类

  • {Chemicalbook} 农药中间体: 杀菌剂中间体: 氨基甲酸酯类杀菌剂
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
  • {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks, Protein Sequencing, Protein Structural Analysis, Proteomics, Reagents for Protein Sequencing

相关文献及参考

  • Short: IV/20C Title: Vapor Pressure and Antoine Coefficients for Nitrogen Containing Organic Compounds Author: Dykyj, J.; Svoboda, J.; Wilhoit, R.C.; Frenkel, M.; Hall, K.R. Editor: Hall, K.R. Source: Landolt-Börnstein, New Series Volume: IV/20C Year: 2001 Keyword: organic compounds; vapor pressure ISBN: 3-540-41060-0 ISBN: 978-3-540-41060-7 Internet Resource: DOI:10.1007/b88812 RefComment: VII, 197 pages
  • Short: IV/8A Title: Enthalpies of Fusion and Transition of Organic Compounds Author: Zhang, Z.-Y.; Frenkel, M.; March, K.N.; Wilhoit, R.C. Editor: Marsh, K.N. Source: Landolt-Börnstein, New Series Volume: IV/8A Year: 1995 Keyword: organic compounds; enthaly of fusion; melting point; phase transition ISBN: 3-540-58854-X ISBN: 978-3-540-58854-2 Internet Resource: DOI:10.1007/b55145 RefComment: VIII, 588 pages.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

Signal word
GHS Symbol
WGK Germany1
Safety Statements
Risk Statements
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R36 Irritating to eyes 刺激眼睛
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P337+P313
  • P302+P352+P312+P362+P364
Hazard statements
  • H227 Combustible liquid 可燃液体
  • H302+H312
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUG1575000
Hazard Codes Xn
Packing GroupII
Hazard Class6.1(a)
Storage condition 2-8°C
UN Number 2927
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2600 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1410 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00201

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,923,1986

其他信息

  • 毒性分级:中毒
  • 方法一:其制备方法是在反应釜中投入丙烯腈,开动搅拌和夹套水,在适宜的温度下通入二甲胺气体至规定量,反应1h取样分析得产品。反应方程式:CH 2 =CHCN+(CH 3 ) 2 NH→(CH 3 ) 2 NCH 2 CH 2 CN
  • Acros Organics:3-(二甲基氨基)丙腈 3-(Dimethylamino)propionitrile, 99%(1738-25-6)
  • MSDS 信息:β-二甲氨基丙腈(1738-25-6).msds
  • 刺激数据:皮肤-兔子 500 毫克/24小时 轻度; 眼睛-兔子 20 毫克/24小时 中度
  • 类别:有毒物品
  • 图谱信息:二甲氨基丙腈(1738-25-6)质谱(MS) 二甲氨基丙腈(1738-25-6)核磁图( 13 CNMR) 二甲氨基丙腈(1738-25-6)核磁图( 1 HNMR) 二甲氨基丙腈(1738-25-6)红外图谱(IR1)
  • 用途一:用于固氮酶细胞分析中蛋白质、酶、核酸分子量的圆盘电泳法的测定
  • 海关编码:29269095
  • MOL 文件:1738-25-6.mol
  • 可燃性危险特性:明火可燃; 受热放出剧毒含腈气体
  • Sigma Aldrich:1738-25-6(sigmaaldrich)
  • 外观性质:无色透明液体,久置空气中易变质。
  • 用途二:β-二甲氨基丙腈是杀菌剂霜霉威的中间体。
  • 上游原料:二甲胺 --> 丙烯腈
  • 二甲氨基丙腈价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80051026 3-二甲氨基丙腈;2-二甲氨基乙基氰; β-二甲氨基丙腈 100ml 38元 2011/04/16 D0662 3-二甲基氨基丙腈 3-Dimethylaminopropionitrile 500ML 2150元 2011/04/16 D0662 3-二甲基氨基丙腈 3-Dimethylaminopropionitrile 25ML 211元
  • 灭火剂:雾状水、泡沫、干粉、二氧化碳、砂土
  • 下游产品:霜霉威 --> N,N-二甲基-1,3-二氨基丙烷
  • 用途三:有机合成中间体,用于合成多种维生素B,也可用作有机溶剂、高分子合成引发剂(促聚剂)以及电镀添加剂的中间体。作为分析试剂,用于固氮酶细胞的分析中蛋白质、酶、核梅分子量的圆盘电泳法的测定。
  • 储运特性:库房通风低温干燥; 与食品、氧化剂、酸类分开储运
  • 职业标准:STEL 10 毫克/立方米
  • 急性毒性:口服-大鼠 LD50: 2600 毫克/ 公斤; 口服-小鼠 LD50: 1500 毫克/ 公斤
  • 方法二:由丙烯腈与二甲胺反应而得。先将丙烯腈在冰冷却下加入二甲胺溶液中,然后进行加热,通过吸收,分馏精馏,收集171-173℃馏分,即得本品。原料消耗定额:丙烯腈670kg/t、二甲胺(40%)1500kg/t。
  • TCI Shanghai:3-(二甲基氨基)丙腈 3-Dimethylaminopropionitrile,>;98.0%(GC)(1738-25-6)
  • F:8

系列性分类


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