2-Chloroethanol (剧毒品,不能销售)2-氯乙醇

CAS 107-07-3 MFCD00002829

化学结构图

107-07-3
SMILES: OCCCl

化学属性

Mol. FormulaC2H5ClO
Mol. Weight80.52
Refractive index1.4410
Density1.202
Autoignition Point797 °F
Vapor Density2.78 (vs air)
Boiling Point129°
Vapor Pressure5 mmHg ( 20 °C)
Melting Point-63°
Flash Point55°(131°F)
TSCAYes
SolubilityMISCIBLE

别名和识别编码

Chemical Name2-Chloroethanol
Synonym Ethylene glycol, chlorohydrin β-Hydroxyeth 2-氯乙醇 { 2-Chloorethanol β-Chloräthanol Glicol monocloridrina 2-Chlor-ethanol {Chemicalbook} 2-chloro-ethanol Glycolmonochloorhydrine ethylenchlorhydrine Aethylenechlorhydrin 2- 2-Chloraethanol Äthylenchlorhydrin Ethylene chlorohydrine Chloroethylowy alkohol 1-chloro-2- {uni_hambur Β-氯乙醇 AKOS BBS-00004331 1-Chloro-2-hydroxyethane 2-Chloro-1-ethanol beta-Chloroethyl alcohol {uni_hambu 2-chloroethanol 2-Chloräthanol 2-CHLORETHANOL Glycol chlorohydrin 2-Chloroethyl alcohol beta-Chloroethanol 亚乙基氯乙醇 Glycol monochlorohydrin Glycomonochlorhydrin 2-Chlorethanol 2-Chloroethanol Ethylenchlorhydrin Ethylene chlorhydrin Monochlorhyd ethylene chlorohydrin Ethyleen-chloorhydrine 2-chloroethylalcohol Ethylene glycol, chlorohyd 二氯乙醇 2-Monochloroethanol C2H5ClO (2-chloro-ethanol) Z-Chloroethanol ethane, 1-chloro-2-hydroxy- chloro-2 ethanol 2-cloroetanolo[italian] 2-Cloroetanolo 2-CHLOROETHANOL 2-氯乙基醇 Ethanol, 2-chloro- Ethylchlorohydrin aethylenechlorhydrin[german] 氯乙醇 NCI-C50135 2-hydroxyethylchloride {uni_ha 2-Hydroxyethyl chloride 2-氯乙醇(0406限出口,属化学武器用化学品)
Beilstein Registry Number0878139
EC Number203-459-7
MDL NumberMFCD00002829
PubChem Substance ID34
CAS Number107-07-3
Merck Number14,3793
Chemical Name Translation(剧毒品,不能销售)2-氯乙醇
Wiswesser Line NotationQ2G
InChIInChI=1S/C2H5ClO/c3-1-2-4/h4H,1-2H2
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分类

  • {uni_hamburg} no charge; alcohol; 1fragment
  • {SNA} All alphabetically sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography, Environmental Standards, Pesticides & Metabolites

相关文献及参考

  • Short: II/25B Title: Structure Data Of Free Polyatomic Molecules: Molecules containing One or Two Carbon Atoms Author: Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D.A.; Vogt, J.; Vogt, N. Editor: Kuchitsu, K. Source: Landolt-Börnstein, New Series Volume: II/25B Year: 1999 Keyword: Free Polyatomic Molecules; Carbon Atoms; Molecules ISBN: 3-540-63645-5 ISBN: 978-3-540-63645-8 Internet Resource: DOI:10.1007/b68834 RefComment: IX, 512 pages. Hardcover Abstract: Volume II/25 is a supplemented and revised edition of the preceding volumes II/7, II/15, II/21 and II/23 containing up to date information on inorganic and organic polyatomic molecules. All experimental methods for the determination of quantitative structural data of free molecules have been considered: microwave, infrared, Raman, electronic and photoelectron spectroscopy as well as electron diffraction. The data obtained by these methods have been critically evaluated and compiled. They are presented separately for each molecule, together with a schematic figure of the structure and the original literature.
  • Short: II/5 Title: Molecular Acoustics Author: Schaaffs, W. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/5 Year: 1967 ISBN: 3-540-03897-3 ISBN: 978-3-540-03897-9 Internet Resource: DOI:10.1007/b19950 RefComment: 321 figs., XII, 286 pages, Hardcover
  • Short: II/6 Title: Molecular Constants from Microwave, Molecular Beam, and Electron Spin Resonance Spectroscopy Author: Demaison, J.; Hüttner, W.; Starck, B.; Buck, I.; Tischer, R.; Winnewisser, M. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/6 Year: 1974 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-05977-6 ISBN: 978-3-540-05977-6 Internet Resource: DOI:10.1007/b19951 RefComment: 153 figs., XIII, 688 pages
  • Short: III/20a Title: Nuclear Quadrupole Resona

安全信息

WGK Germany3
RTECSKK0875000
GHS Symbol
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H300 Fatal if swallowed 吞食致命
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word Danger
Packing GroupI
UN Number 1135 UN 1135 6.1/PG 1 UN1135
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒
  • R10 Flammable 易燃
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R11 Highly flammable 非常易燃
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
Safety Statements
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭,置于通风良好的场所;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S1/2 None 上锁保管并避免儿童触及;
Hazard Codes T+ T+,T,F
Hazard Class6.1
Storage condition 2-8°C
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Gastrointestinal - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 23,259,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 98 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 15(2),54,

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 81 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 60,568,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 43(

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2914 umol/L
REFERENCE :
   EMMUEG Envi

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 ug/kg
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 43(8),13,1978

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 40 gm/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   30,9,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,367,1974

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 980 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   14,165,1989

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 mg/m3
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 36(11),9,1971

{hazard_com}

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1100 mg/kg
SEX/DURATION            : female 6-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - hepatobiliary system
REFERENCE :
   JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
   Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
   New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 17,381,1982

其他信息

  • 防护措施:有毒,在机体组织内水解产生氯化氢。吸入高浓度氯乙醇蒸气或者经皮
  • 方法一:氯乙醇有多种制备方法。环氧乙烷与盐酸反应,是实验室制备氯乙醇的最方便方法。实际上,乙二醇与二氯化硫反应得到氯乙醇,也是实验室制备氯乙醇的方法之一。如果环氧乙烷与无水氯化氢在氯化铁和磷酸二氢钠存在下反应,则无副产乙二醇生成,适用于制造高纯度氯乙醇。氯乙醇的工业生产方法基本上还是1991年Gomberg提出的方法,将乙烯和氯同时通入水中,氯与水反应生成次氯酸,次氯酸与乙烯加成即得氯乙醇。
  • 2-氯乙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80033528 2-氯乙醇(剧毒) 500ml 110元 2010/06/21 180960010 2-氯乙醇 2-Chloroethanol 99+% 1 LT 532元 2010/06/21 180960025 2-氯乙醇 2-Chloroethanol 99+% 2.5 LT 1271元
  • 类别:农药
  • 图谱信息:2-氯乙醇(107-07-3)红外图谱(IR1) 2-氯乙醇(107-07-3)Raman光谱 2-氯乙醇(107-07-3)核磁图( 1 HNMR) 2-氯乙醇(107-07-3)红外图谱(IR2) 2-氯乙醇(107-07-3)质谱(MS) 2-氯乙醇(107-07-3)核磁图( 13 CNMR)
  • 下游产品:1-(2-(4-溴苯氧基)乙基)吡咯烷 --> 氯化胆碱 --> 胆碱 --> 3-羟基丙腈 --> N-(2-氯乙基)吡咯烷盐酸盐 --> 1-(2-氨乙基)吡咯烷 --> 1-(2-吡啶酮乙基)哌嗪 --> 荧光增白剂 NR,赫司特鲁克斯 --> N,N'-双(2-羟乙基)哌嗪 --> 2-巯基乙醇 --> 磷酸三(2-氯乙基)酯 --> 二(2-羟乙基)硫醚 --> 2-甲硫基乙醇 --> 甲基丙烯酸羟乙酯 --> 4-(2-羟基乙氧基)苯甲醛 --> 氯化乙酰胆碱 --> N-甲基-N-羟乙基苯胺 --> 引发剂 BPPD --> 咳安定 --> 2-(2,4,6-三氯苯氧基)乙基氯 --> 卡巴胆碱 --> 乙基2-羟乙基硫醚 --> 双苯甲醇-β-氯乙基醚 --> 均相氯乙醇型强碱性阴离子交换膜 --> 氯甲酸氯乙酯 --> 2-氟乙醇 --> 氯代乙氨基甲酸乙酯 --> 苯海拉明 --> 1-溴-2-氟乙烷 --> 1-溴-2-氯乙烷 --> 对甲苯磺酸-β-氯乙酯 --> 阿德福韦酯 --> 2-碘乙醇 --> 曲克芦丁
  • MSDS 信息:2-氯乙醇(107-07-3).msds
  • 可燃性危险特性:明火、高温、强氧化剂可燃; 受高热分解产生剧毒光气和氯化物烟雾
  • 用途一:用于制造环氧乙烷、合成橡胶、染料、医药及农药等,也是有机溶剂
  • Acros Organics:2-氯乙醇 2-Chloroethanol, 99+%(107-07-3)
  • F:21
  • MOL 文件:107-07-3.mol
  • 上游原料:盐酸 --> 曙光红(四溴荧光素) --> 二氯化硫 --> 次氯酸 --> 无水氯化氢
  • 用途四:氯乙醇是重要的有机溶剂和有机合成原料。以前氯乙醇的最大用途是生产环氧乙烷,现在绝大部分氯醇法环氧乙烷装置已被直接氧化法所取代。现在氯乙醇的主要用途是作聚硫橡胶的原料以及染料、农药、医药的中间体。氯乙醇与硫化钠反应可得硫代二甘醇,是纺织品的印染溶剂,亦是还原染料,聚亚基二氯的增塑剂。氯乙醇衍生物β,β'二氯二乙基醚的是合成芥子气毒气的原料,亦是精制润滑油的萃取溶剂,也用作土壤杀菌剂。氯乙醇可合成二氯乙基缩甲醛,是生产聚硫弹性体的原料之一。氯乙醇与乙炔反应可生成氯乙基乙烯基醚,是生成聚丙烯酸性体的原料。氯乙醇用60%硝酸氧化能以90%收率生成氯乙酸,用于合成染料、氨基乙酸、丙二酸酯,羟基乙酸、肾上腺素、2,4-二氯苯氧基乙酸、乐果、羧甲基纤维素、费洛那尔安眠药、氯乙酰胺、碘乙酰胺、N-甲基氨基乙酸钠。在医药工业中,氯乙醇
  • Sigma Aldrich:107-07-3(sigmaaldrich)
  • 防护
  • 蒸气压:5 mm Hg ( 20

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