• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Selenium Compounds
• {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment

产品应用

• 用于合成烯丙基醇、烯丙基醚、乙酸酯和α，β-不饱和羰基化合物。

相关文献及参考

• For introduction of the phenylseleno group by Michael addition, phenylselenol can be generated in situ by borohydride cleavage: Synthesis, 664 (1980).
• For a comprehensive review of the preparation of ɑß-unsaturated carbonyl compounds and nitriles by selenoxide elimination, see: Org. React., 44, 1 (1993). Compare also Phenyl­selenenyl­ bromide, A11906 and Phenyl­selenenyl­ chloride, A12751.
• Reagent for ɑ-phenylselenation of enolates. The products are readily oxidized to the selenoxides which undergo ambient temperature Cope-type elimination, providing a mild method for the introduction of ɑß-unsaturation into, e.g. ketones: J. Am. Chem. Soc., 97, 5434 (1975):
• Short: EINECS
• Short: III/5a
• Beilstein:6,346
• Oxidation of diphenyl diselenide by persulfate in the absence of a nucleophilic counter-ion generates the phenylselenium cation, which adds to alkenes. Molecules with a suitably placed nucleophilic site (alkene, hydroxyl, carbonyl, carboxyl, etc.) can then undergo intramolecular cyclization: J. Org. Chem., 55, 429 (1990); J. Chem. Soc. Perkin 1, 1989 (1993); Synlett, 373 (1994):
• Short: III/35G
• For reviews of the application of organoselenium reagents in organic synthesis, see: Tetrahedron, 34, 1049 (1978); Acc. Chem. Res., 12, 22 (1979); 17, 28 (1984). Monograph: Organoselenium Chemistry, D. Liotta, ed., Wiley, N.Y. (1987).

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#05657

其他信息

• 职业标准:TLV-TWA 0.2 (硒) 毫克/ 立方米; STEL 0.3 (硒) 毫克/ 立方米
• TCI Shanghai:二苯基二硒醚 Diphenyl Diselenide,>;96.0%(GC)(1666-13-3)
• 二苯基二硒醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 XW16661331 二苯二硒醚 5g 216元 2011/08/23 XW16661332 二苯二硒醚 25g 659元 2011/08/23 XW16661333 二苯二硒醚 100g 1996元
• 外观性质:黄色固体, 无气味。
• 可燃性危险特性:明火可燃;高热分解有毒硒化物;与酸起作用
• 毒性分级:剧毒
• 方法一:溴苯和镁屑在绝对乙醚中制成苯基溴化镁，然后分批加入硒粉，使反应物维持激烈的回流状态。半小时后，加水破坏剩余的格氏试剂，冷却，搅拌下向混合物滴加溴，再慢慢加入氯化铵水溶液。过滤，滤饼用乙醚用乙醚洗涤。合并滤液和洗涤液，蒸除溶剂，使析出的固体溶于热己烷，滤去不溶物，滤液冷至6℃，过滤，干燥，得二硒二苯
• Acros Organics:二苯基联二硒 Diphenyl diselenide, 99%(1666-13-3)
• 急性毒性:静注- 小鼠 LD50: 28 毫克/ 公斤
• 溶于热醇、醚和二甲苯。不溶于水。
• MSDS 信息:二苯基二硒(1666-13-3).msds
• Sigma Aldrich:1666-13-3(sigmaaldrich)
• 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂、酸类分开存放
• Alfa Aesar:二苯基二硒醚,98% Diphenyl diselenide, 98%(1666-13-3)
• 用途一:用于合成烯丙基醇、烯丙基醚、乙酸酯和α，β-不饱和羰基化合物。
• 灭火剂:泡沫、雾状水、砂土
• MOL 文件:1666-13-3.mol
• 上游原料:溴苯 --> 格氏试剂 --> 硒
• 类别:有毒物品