o-Phthaldialdehyde 邻苯二甲醛

CAS 643-79-8 MFCD00003335

化学结构图

643-79-8
SMILES: O=Cc1ccccc1C=O

化学属性

Mol. FormulaC8H6O2
Mol. Weight134.13
Melting Point55-58°C
Density1.13
Flash Point132°C
TSCAYes
Boiling Point266.1°C at 760 mmHg
Solubility可溶
Appearance powder 黄色针状晶体。熔点54-56℃。
Stability对空气,光线和湿度敏感

别名和识别编码

Chemical Nameo-Phthaldialdehyde
CAS Number643-79-8
Alfabeta NameBENZENEDICARBOXALDEHYDE 12--,
MDL NumberMFCD00003335
Synonym Benzene-1,2-dicarboxaldehyde {LY} Benzene-1,2-dicarboxaldehyde {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzene-1,2-dicarboxaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID4807
EC Number211-402-2
Beilstein Registry Number7,674
Reaxys-RN878317
Merck Number7368
Chemical Name Translation邻苯二甲醛
Wiswesser Line NotationVHR BVH
LabNetwork Molecule IDLN00175092
InChIInChI=1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
Canonical SMILESO=CC1=CC=CC=C1C=O
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分类

  • {SNA} Aldehydes,
  • {SNA} Aldehydes, Alphabetical, Amino Acid Analysis, Amino Acids, Building Blocks, C8, Carbohydrate Labels, Carbohydrate Labels for Chromatography, Carbonyl Compounds, Chemical Synthesis, Derivatization Reagents, Derivatization Reagents HPLC,

产品应用

  • 1、化学领域分析试剂:作为胺类生物碱试剂,用于荧光法测定伯胺和肽键分解物。
  • 2、有机合成:也是医药中间体
  • 3、荧光试剂,用于柱前HPLC分离氨基酸衍生物,流式细胞测量蛋白质的硫醇基团。

相关文献及参考

  • Short: EINECS
  • Short: III/5a
  • Reagent for precolumn derivatization of amino acids: J. Chromat., 359, 231 (1986).
  • Merck: 14,7368 Beilstein:7,674
  • Merck: 14,7368

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes T,N C
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTH6950000
Precautionary statements
  • P301+P310+P330
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338
  • P405 Store locked up. 上锁保管。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P304+P340+P310
  • P303+P361+P353
  • P305+P351+P338+P337+P313
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P302+P352+P333+P313+P362+P364
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
Signal word
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R34 Causes burns 会导致灼伤
UN Number 2811
Storage condition 2-8°C, stored under nitrogen {LY} 2-8°C, stored under nitrogen Air Sensitive {} {LY} 2-8°C, stored under nitrogen {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C,
Packing GroupIII
Hazard Class6.1
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
   (Paris, France)  V.1-261, 1835-1965.  For publisher information, see CRASEV.
    Volume(issue)/page/year: 246,851,1958

其他信息

  • Fluoraldehyde Reagent Solution contains OPA (o-phthalaldehyde), which reacts with primary amines of amino acids, peptide and proteins to enable fluorescent detection and quantitation. The reagent that can be used as a protein or peptide assay reagent or as a pre- or post-column detection reagent for amino acid analysis (HPLC). Reaction of OPA with proteins and peptides yields linear results over a wide range of concentrations. The Fluoraldehyde Reagent Solution is supplied ready to use and enables fast quantitation of proteins or peptides in solution.
  • 检测方法:GC
  • 海关编码:29122900
  • 用途一:主要用于医药、染料等
  • MOL 文件:643-79-8.mol
  • 存储注意事项:光敏感;湿度敏感;氮气保护
  • 下游产品:并五苯 --> 拉西地平 --> 2,3-萘基二缩醛
  • Alfa Aesar:邻苯二甲醛,98% Phthaldialdehyde, 98%(643-79-8)
  • Acros Organics:邻苯二甲醛 1,2-Phthalicdicarboxaldehyde,98+%(643-79-8)
  • 用途二:用于医药检验
  • 敏感性:Air Sensitive
  • MSDS 信息:1,2-Phthalic dicarboxaldehyde(643-79-8).msds
  • TCI Shanghai:1,2-苯二甲醛[用于高效液相色谱标记] o-Phthalaldehyde [for HPLC Labeling],>;99.0%(GC)(643-79-8)
  • 邻苯二甲醛价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30147323 邻苯二甲醛(+4℃) 10g 131.3元 2011/08/23 L0194802 邻苯二甲基二甲醛 25g 1115元 2011/04/16 P0280 1,2-苯二甲醛[用于高效液相色谱标记] o-Phthalaldehyde [for HPLC Labeling] 100G 4310元
  • color:yellow
  • 用途三:该品是医药中间体,最新的外用高效安全抗菌消毒剂,作为医院的内窥镜手术用器械消毒灭菌,可用于合成新抗血小板聚集药吲哚波芬,也是化学领域分析试剂。
  • 对光和空气敏感。能随水蒸气挥发。溶于水、乙醇、乙醚和有机溶剂,微溶于石油醚。有刺激性。
  • Highlights:
  • F:1-8-10
  • 用途四:1、化学领域分析试剂:作为胺类生物碱试剂,用于荧光法测定伯胺和肽键分解物。2、有机合成:也是医药中间体3、荧光试剂,用于柱前HPLC分离氨基酸衍生物,流式细胞测量蛋白质的硫醇基团。
  • {A
  • Hazard Note:Irritant/Air Sensitive
  • Sigma Aldrich:643-79-8(sigmaaldrich)
  • 图谱信息:邻苯二甲醛(643-79-8)红外图谱(IR2) 邻苯二甲醛(643-79-8)核磁图( 1 HNMR) 邻苯二甲醛(643-79-8)红外图谱(IR1) 邻苯二甲醛(643-79-8)核磁图( 13 CNMR) 邻苯二甲醛(643-79-8)质谱(MS)

系列性分类