• P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
• P301+P312+P330

• H302 Harmful if swallowed 吞食有害
• H302+H312+H332

• S22 Do not breathe dust 不要吸入粉尘；
• S36 Wear suitable protective clothing 穿戴适当的防护服；
• S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
• S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

• R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
• R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
• R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Blood - hemorrhage
REFERENCE :
   SRTCAC Science Reports of the Research Institutes, Tohoku University, Series
   C: Medicine. (Tohoku University, Research Institute for Tuberculosis and
   Cancer, 4-1 Seiryo-machi, Sendai, Japan)  V.1-   1949-
   Volume(issue)/page/year: 36(1-4),10,1989

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AJSNAO American Journal of Syphilis and Neurology.  (St. Louis, MO) V.1-19,
   1917-35.  For publisher information, see AJSGA3. Volume(issue)/page/year:
   1,347,1917

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 12,749,1983

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AJSNAO American Journal of Syphilis and Neurology.  (St. Louis, MO) V.1-19,
   1917-35.  For publisher

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,53,1995

TYPE OF TEST            : S

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 20 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 319,205,1993

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Mammal - species unspecified Kidney
DOSE/DURATION           : 10 umol/L
REFERENCE :
   JCLBA3 Journal of Cell Biology.  (Rockefeller Univ. Press, 1230 York Ave.,
   New York, NY 10003) V.12-    1962-  Volume(issue)/page/year: 79,573,1978

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 1 mg/L
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   30,307,1992

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,53,1995

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211,

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 33750 ug/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   LIFSAK Life Sciences.  (Pergamon Press Inc., Maxwell House, Fairview Park,
   Elmsford, NY 10523) V.1-8, 1962-69; V.14-    1974- Volume(issue)/page/year:
   55,1267,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 300 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   BTERDG Biological Trace Element Research.  (Humana Press Inc., POB 2148,
   Clifton, NJ 07015) V.1-    1979-  Volume(issue)/page/year: 30,219,1991