Pyridine-2(1H)-Thione 吡啶-2(1H)-硫酮

CAS 2637-34-5 MFCD00006285

化学结构图

2637-34-5
SMILES: Sc1ccccn1

化学属性

Mol. FormulaC5H5NS
Mol. Weight111.16
Density1.2
Melting Point127-130 °C
TSCAYes
Flash Point125 ºC
Solubility50 G/L (20 ºC)
Stability对空气敏感
Boiling Point184.9±23.0 °C at 760 mmHg

别名和识别编码

Chemical NamePyridine-2(1H)-Thione
CAS Number2637-34-5
Synonym 2-Mercaptopyridine {LY} 2-Mercaptopyridine {} {LY} 2-Mercaptopyridine {} {} {LY} 2-Mercaptopyridine {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} { {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercaptopyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number220-131-9
Beilstein Registry Number105787
MDL NumberMFCD00457440
PubChem Substance ID87572331
Chemical Name Translation吡啶-2(1H)-硫酮
Reaxys-RN105787
Wiswesser Line NotationT6NJ BSH
InChIKeyWHMDPDGBKYUEMW-UHFFFAOYSA-N
LabNetwork Molecule IDLN00008742
InChIInChI=1S/C5H5NS/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)
Canonical SMILESS=C1C=CC=CN1
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分类

  • Sulfur & Selenium Compounds
  • Heterocycles
  • {SNA} Building Blocks, C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; 6RingOnly; 6ring; 1fragment

产品应用

  • 用作金属络合物中的配体

相关文献及参考

  • Beilstein:21,45
  • Short: III/5a
  • Titanium enolates of S-acyl derivatives react with imines in a one pot synthesis of ß-lactams: J. Org. Chem., 57, 4155 (1992).
  • S-Acyl derivatives react with Grignard reagents in a high-yielding synthesis of ketones: J. Am. Chem. Soc., 95, 4763 (1973):
  • Li, Y. et al.: J. Appl. Polym. Sci., 104, 2205 (2007).

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSUT9600000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition 2-8°C, stored under nitrogen {LY} 2-8°C, stored under nitrogen Air Sensitive {} {LY} 2-8°C, stored under nitrogen {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sto
Hazard Codes Xn Xi Xi,Xn
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 93,143,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

其他信息

  • Acros Organics:2-巯基吡啶 2-Mercaptopyridine, 99%(2637-34-5)
  • 敏感性:Air Sensitive
  • 2-疏基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0246 2-巯基吡啶 2-Mercaptopyridine 100G 2200元 2014/06/02 M0246 2-巯基吡啶 2-Mercaptopyridine 25G 731元 2010/06/21 125540250 2-疏基吡啶 2-Mercaptopyridine 98% 25 GR 682元
  • TCI Shanghai:2-巯基吡啶 2-Mercaptopyridine,>;95.0%(T)(2637-34-5)
  • 下游产品:S-甲基-S-(2-吡啶基)亚磺酰亚胺 --> 2-砒啶磺酰氯盐酸盐 --> 2-吡啶磺酸
  • F:10-23
  • Alfa Aesar:2-巯基吡啶,98% 2-Mercaptopyridine, 98%(2637-34-5)
  • 用途一:用作有机合成中间体
  • MOL 文件:2637-34-5.mol
  • Sigma Aldrich:2637-34-5(sigmaaldrich)
  • 图谱信息:2-疏基吡啶(2637-34-5)质谱(MS) 2-疏基吡啶(2637-34-5)核磁图( 13 CNMR) 2-疏基吡啶(2637-34-5)红外图谱(IR2) 2-疏基吡啶(2637-34-5)核磁图( 1 HNMR) 2-疏基吡啶(2637-34-5)红外图谱(IR1)
  • MSDS 信息:2-Mercaptopyridine(2637-34-5).msds

系列性分类


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