2-Amino-3-methylpyridine 2-氨基-3-甲基吡啶

CAS 1603-40-3 MFCD00006320

化学结构图

1603-40-3
SMILES: Cc1cccnc1N

化学属性

Mol. FormulaC6H8N2
Mol. Weight108.14
Density1.073
Refractive indexn20/D 1.5823(lit.)
Boiling Point220.9°C at 760 mmHg
Melting Point29-31°C
Flash Point118°C
TSCAYes
Solubility易溶于水,溶于多数有机溶剂。
Stability易吸潮

别名和识别编码

Chemical Name2-Amino-3-methylpyridine
CAS Number1603-40-3
Alfabeta NameAMINOMETHYLPYRIDINE 23---
MDL NumberMFCD00006320
EC Number216-501-4
Beilstein Registry Number107892
Synonym 2-Amino-3-methylpyridine {LY} 2-Amino-3-methylpyridine {} {LY} 2-Amino-3-methylpyridine {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-3-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID87562036
Chemical Name Translation2-氨基-3-甲基吡啶
Reaxys-RN107892
Wiswesser Line NotationT6NJ BZ C1
LabNetwork Molecule IDLN00222308
InChIInChI=1S/C6H8N2/c1-5-3-2-4-8-6(5)7/h2-4H,1H3,(H2,7,8)
Canonical SMILESNC1=NC=CC=C1C
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分类

  • {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

相关文献及参考

  • Beilstein:22(2)342

安全信息

Warnings IRRITANT
Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R33 Danger of cumulative effects 有累积作用的危险
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P310+P330
  • P302+P350
  • P302+P352+P310+P361+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P307+P311
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P332+P313
  • P337+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H331 Toxic if inhaled 吸入中毒
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUS1850000
Packing GroupIII
UN Number 2811 UN 2811 6.1/PG 3
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light Hygroscopic {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from li
Hazard Codes 6.1 T
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#01585

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AJEBAK Australian Journal of Experimental Biology and Medical Science.
   (Adelaide, S.A., Australia) V.1-64, 1924-86.  Volume(issue)/page/year:
   36,491,1958

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 650 ppm/6H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,841,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,841,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIE

其他信息

  • 图谱信息:2-氨基-3-甲基吡啶(1603-40-3)核磁图( 1 HNMR) 2-氨基-3-甲基吡啶(1603-40-3)红外图谱(IR1) 2-氨基-3-甲基吡啶(1603-40-3)核磁图( 13 CNMR) 2-氨基-3-甲基吡啶(1603-40-3)质谱(MS)
  • 2-氨基-3-甲基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0400 2-氨基-3-甲基吡啶 2-Amino-3-methylpyridine 25G 198元 2014/06/02 A0400 2-氨基-3-甲基吡啶 2-Amino-3-methylpyridine 500G 1290元 2010/06/21 104381000 2-氨基-3-甲基吡啶 2-Amino-3-picoline 96% 100 GR 353元
  • 储运特性:库房通风低温干燥
  • 急性毒性:口服-大鼠LD50: 100 毫克/公斤; 皮下-小鼠LD50: 36 毫克/公斤
  • 毒性分级:高毒
  • TCI Shanghai:2-氨基-3-甲基吡啶 2-Amino-3-picoline,>;98.0%(GC)(1603-40-3)
  • Alfa Aesar:2-氨基-3-甲基吡啶,97% 2-Amino-3-methylpyridine, 97%(1603-40-3)
  • Acros Organics:3-甲基-2-氨基吡啶 2-Amino-3-picoline, 96%(1603-40-3)
  • 敏感性:Hygroscopic
  • 检测方法:HPLC
  • 下游产品:2-氨基-4-甲氧基吡啶-3-羧酸 --> 3-甲基-2-氯-5-氨基吡啶 --> 3-甲基-4-甲氧基吡啶-2-胺 --> 3-甲基-4-甲氧基-2-氯吡啶 --> 2-甲基-7-氮杂吲哚 --> 3-甲基-4-甲氧基-2-氯吡啶 N-氧化物 --> 2-氨基-5-羟基吡啶 --> 2-氯-5-碘-3-甲基吡啶 --> 3-甲基-4-硝基-2-氯吡啶 N-氧化物 --> 2-乙酰氨基-吡啶-3-羧酸 --> 2-溴-3-甲基-5-吡啶硼酸 --> 2-(三氟甲基)烟酸 --> 2-溴-3-甲基吡啶 --> 2-硝基烟酸 --> 2-氯-3-甲基吡啶-5-硼酸 --> 2-氨基-3-甲基-5-溴吡啶 --> 2-硝基-3-甲基吡啶 --> 5-甲基-6-氨基吡啶-3-乙腈 --> 2,5-二溴吡啶-3-甲醛 --> 2-氨基-3-甲基-5-硝基吡啶 --> 2-氨基-5-硝基吡啶-3-羧酸 --> 2-氨基-3-羟甲基吡啶 --> 2-氨基-3-甲基-5-氯吡啶 --> 2-羟基-5-硝基3-甲基吡啶 --> 2-氨基烟酸乙酯 --> 2-氯-3-甲基-5-溴吡啶 --> 吡嘧司特 --> 3-甲基-2-乙酰氨基吡啶 --> 5-甲基-6-氨基吡啶-3-磺酸
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • 溶于水。
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • 外观性质:黄色结晶。
  • MSDS 信息:氨基-3-甲基吡啶(1603-40-3).msds
  • MOL 文件:1603-40-3.mol
  • 海关编码:29333999
  • 类别:有毒物品

系列性分类


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