CAS 80-08-0 MFCD00007887-4-Aminophenyl Sulfone 4-氨基苯砜 -LabNovo

4-Aminophenyl Sulfone 4-氨基苯砜

CAS 80-08-0 MFCD00007887

化学结构图

SMILES: NC1C=CC(=CC=1)S(=O)(=O)C1C=CC(N)=CC=1

化学属性

Mol. Formula	C12H12N2O2S
Mol. Weight	248.30
Density	1.361
Melting Point	173-178°C
TSCA	T
Solubility	<0.1 G/100 ML AT 20 ºC
Stability	对湿度敏感
Boiling Point	511.7°C at 760 mmHg

别名和识别编码

Chemical Name	4-Aminophenyl Sulfone
CAS Number	80-08-0
Alfabeta Name	AMINOPHENYLSULFONYLANILINE 44[]()--
MDL Number	MFCD00007887
Synonym	Dapsone {LY} Dapsone {} {LY} Dapsone {} {} {LY} Dapsone {} {} {} {LY} Dapsone {} {} {} {} {LY} Dapsone {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dapsone {} {} {} {} {} {} {} {} {} {} {}
EC Number	201-248-4
Beilstein Registry Number	788055
PubChem Substance ID	87566830
Reaxys-RN	788055
Merck Number	2822
Chemical Name Translation	4-氨基苯砜
Wiswesser Line Notation	ZR DSWR DZ
LabNetwork Molecule ID	LN00142376
Canonical SMILES	O=S(C1=CC=C(N)C=C1)(C2=CC=C(N)C=C2)=O

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品牌质保精细包装现货库存一流品牌服务

产品应用

用于合成聚砜酰胺树脂及其他聚合物，抗麻风病类药。

安全信息

Warnings IRRITANT

Signal word Warning {} {} {} {} {} {} {} {TCI}

GHS Symbol

WGK Germany1

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R22 Harmful if swallowed 吞咽有害
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P273 Avoid release to the environment. 避免释放到环境中。
P301+P312
P301+P312+P330
P305+P351+P338
P305+P351+P338+P337+P313
P307+P311
P308+P311
P332+P313
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302 Harmful if swallowed 吞食有害

Hazard Codes Xn

RTECSBY8925000

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

Packing GroupIII

Hazard Class9

UN Number 3249 3077

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 21840 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Blood - tumors
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   25,619,1987

{h

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 gm/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Blood - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-20,1977

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 39 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Blood - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-20,1977

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 78450 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Endocrine - thyroid tumors
REFERENCE :
   ALEPA8 Acta Leprologica.  (3, pl. Claparede, 1205 Geneva, Switzerland) No.1-
      1960-  Volume(issue)/page/year: 53,11,1973

TYPE OF TEST            : TDLo - Lowest published tox

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,213,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   28,313,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   HUTODJ H

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 300 mg/kg/21W-I
TOXIC EFFECTS :
   Blood - eosinophilia
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 343,860,1994

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 4 mg/L
REFERENCE :
   IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases.
   (POB 1097, Bloomfield, NJ 07003)  V.1-    1933-  Volume(issue)/page/year:
   43,41,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2100 mg/kg
SEX/DURATION            : male 6 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 81,259,1987

其他信息

Alfa Aesar:4,4'-二氨基二苯砜,98% 4,4'-Diaminodiphenyl sulfone, 98%(80-08-0)
MOL 文件:80-08-0.mol
类别:有毒物品
职业标准:STEL 5 毫克/立方米
灭火剂:二氧化碳、砂土、干粉
用途四:为治疗麻风病的首选药物，也可与其他抑制麻风病药联合应用
海关编码:29309070
检测方法:HPLC.NMR
用途一:用作气相色谱固定液、有机合成中间体及环氧树脂固化剂
用途二:要用于治疗各型麻风病。工业上用作环氧树脂的熟化剂等。
急性毒性:口服-大鼠 LD50: 1000 毫克/公斤; 口服-小鼠 LD50: 250 毫克/公斤
用途三:用作医药、高分子材料中间体
储运特性:库房通风低温干燥; 与食品原料分开储运
MSDS 信息:4,4'-二氨基二苯砜(80-08-0).msds
不溶于水，溶于稀盐酸、乙醇、甲醇和丙酮。
Sigma Aldrich:80-08-0(sigmaaldrich)
图谱信息:4,4'-二氨基二苯砜(80-08-0)红外图谱(IR2) 4,4'-二氨基二苯砜(80-08-0)红外图谱(IR1) 4,4'-二氨基二苯砜(80-08-0)核磁图( 1 HNMR) 4,4'-二氨基二苯砜(80-08-0)核磁图( 13 CNMR) 4,4'-二氨基二苯砜(80-08-0)质谱(MS)
外观性质:白色或微黄色结晶性粉末，无气味，味苦。
TCI Shanghai:4,4'-二氨基二苯砜 Bis(4-aminophenyl) Sulfone,>;97.0%(T)(80-08-0)
下游产品:
毒性分级:高毒
用途五:用于合成聚砜酰胺树脂及其他聚合物，抗麻风病类药。
Acros Organics:4,4'-二氨基二苯砜 4-Aminophenyl sulfone, 97%(80-08-0)
4,4'-二氨基二苯砜价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 81006126 4，4-二氨基二苯砜 100g 46.2元 2011/04/16 D0089 双(4-氨苯基)砜 Bis(4-aminophenyl) Sulfone 25G 250元 2011/04/16 D0089 双(4-氨苯基)砜 Bis(4-aminophenyl) Sulfone 500G 1340元

4-Aminophenyl Sulfone 4-氨基苯砜

CAS 80-08-0 MFCD00007887

化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

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化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

系列性分类

相关产品推荐

Products Indices

Mailings

Contact

链接