Triethylene glycol dimethyl ether 三乙二醇二甲醚

CAS 112-49-2 MFCD00008504

化学结构图

112-49-2
SMILES: COCCOCCOCCOC

化学属性

Mol. FormulaC8H18O4
Mol. Weight178
Density0.986
Refractive index1.4220 to 1.4240
Flash Point108°C(lit.)
TSCAYes
Boiling Point216
Melting Point-45
Autoignition Point375 °F
Vapor Density>;4.7 (vs air)
Solubility可溶
Stability易吸潮
Danger-Level-
pH-:-
Redox-

别名和识别编码

Chemical NameTriethylene glycol dimethyl ether
CAS Number112-49-2
Synonym (CH3O(CH2)2OCH2)2 1,2-BIS(2-METHOXYETHOXY)ETHANE 1,2-Bis(2-methoxyethoxy)ethane, Dimethyltriglycol, Triglyme 1,2-Bis(2-methoxyethoxy)ethane; Triglyme 1,2-bis-(2-methoxy-ethoxy)-ethane 2,5,8,11-TETRAOXADODECANE 2,5,8,11-tetraoxadodecane 2-(2-Methoxyethoxy)ethyl 2-methoxyethyl ether Ansul Ether 161 Ansul ether 161 DIMETHYLTRIGLYCOL Dimethyltriglykol Glyme-4 TEGDME Triethylene glycol dimethyl ether Triglyme ethane, 1,2-bis(2-methoxyethoxy)- ethane,1,2-bis(2-methoxyethoxy)- glyme 4 triethylene glycol dimethyl ether triglyme {} {} {Ch 三乙二醇二甲醚 三乙二醇二甲醚/三甘醇二甲醚 三甘醇二甲醚 三甘醇二甲醚;三乙二醇二甲基醚;1,2-双(2-甲氧基乙氧基)乙烷;2,5,8,11-四氧杂十二烷
MDL NumberMFCD00008504
EC Number203-977-3
Merck Number9692
Beilstein Registry Number1700630
PubChem Substance ID8189
Reaxys-RN1700630
Chemical Name Translation三乙二醇二甲醚
Wiswesser Line Notation1O2O2O2O1
LabNetwork Molecule IDLN00195704
InChIInChI=1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3
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分类

  • Aliphatics
  • {uni_hamburg} no charge; ether; 1fragment
  • {SNA} Building Blocks, C10, Chemical Synthesis, Ethers, Organic Building Blocks, Oxygen Compounds

产品应用

  • It is used as a solvent.

相关文献及参考

  • Short: III/47
  • Merck:14,9692 Beilstein: 1,IV,2401
  • Has been used as solvent in a simplified Wittig synthesis, with anhydrous K 2 CO 3 as base and the phosphonium salt, such as Methyl­triphenyl­phosphonium bromide, A15878, acting as both reactant and phase-transfer catalyst: Synth. Commun., 22, 513 (1992).
  • Short: III/38B
  • Merck:14,9692
  • Useful aprotic solvent with chelating properties.

安全信息

RTECSXF0665000
Risk Statements
  • R19 May form explosive peroxides 可能生成易爆的过氧化物质
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Storage condition 充氩保存 Hygroscopic
GHS Symbol
WGK Germany3
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H303 May be harmfully swallowed 吞食可能有害
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P308+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Hazard Codes T
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7500 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB86-103215

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7500 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   num

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 5 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 31,53A,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 28 gm/kg
SEX/DURATION            : female 6-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis.  (Alan R. Liss, Inc.,
   41 E. 11th St., New York, NY 10003)  V.1-    1980- Volume(issue)/page/year:
   7,29,1987

Restrict -

其他信息

  • Sigma Aldrich:112-49-2(sigmaaldrich)
  • 图谱信息:三甘醇二甲醚 (112-49-2)质谱(MS) 三甘醇二甲醚 (112-49-2)核磁图( 13 CNMR) 三甘醇二甲醚 (112-49-2)核磁图( 1 HNMR) 三甘醇二甲醚 (112-49-2)Raman光谱 三甘醇二甲醚 (112-49-2)红外图谱(IR1) 三甘醇二甲醚 (112-49-2)红外图谱(IR2)
  • F:3
  • 蒸气密度:>;4.7 (vs air)
  • 敏感性:Hygroscopic
  • MOL 文件:112-49-2.mol
  • 溶于水及烃类溶剂。
  • 外观性质:无色透明液体,溶于水及烃类溶剂。密度:0.986熔点:-45 °C沸点:216 °C折光率:1.422-1.424闪点:113 °C
  • Alfa Aesar:三乙二醇二甲醚,99% Triethylene glycol dimethyl ether, 99%(112-49-2)
  • TCI Shanghai:三乙二醇二甲基醚 Triethylene Glycol Dimethyl Ether,>;98.0%(GC)(112-49-2)
  • Acros Organics:三乙二醇二甲醚/三甘醇二甲醚 Triethylene glycol dimethyl ether, stabilized, 99%(112-49-2)

系列性分类