N-Acetylprocainamide N-乙酰普鲁卡因胺
CAS 32795-44-1 MFCD00009052
化学结构图
SMILES: CC(=O)NC1C=CC(=CC=1)C(=O)NCCN(CC)CC
化学属性
| Mol. Formula | 4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2 |
|---|---|
| Mol. Weight | 277.36 |
| Melting Point | 138-140 °C(lit.) |
别名和识别编码
| Chemical Name | N-Acetylprocainamide |
|---|---|
| MDL Number | MFCD00009052 |
| PubChem Substance ID | 24856329 |
| Synonym | 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide N-Acetylprocainamide N-Acetyloprokainamid N-乙酰普鲁卡因胺 Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)- Acecainide NAPA Acekainid |
| Chemical Name Translation | N-乙酰普鲁卡因胺 |
| Wiswesser Line Notation | 2N2&2MVR DMV1 |
| Beilstein Registry Number | 2868559 |
| CAS Number | 32795-44-1 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Amides, Building Blocks, C8 to C20+, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
- {SA} Amides, Building Blocks, C8 to C20+, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
相关文献及参考
- [2]. Plass H, et al. Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jun;371(6):492-9.
- [1]. Nakahara T, et al. Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. Eur J Pharmacol. 2001 Mar 9;415(1):73-8.
- [1]. Nakahara T, et al. Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. Eur J Pharmacol. 2001 Mar 9;415(1):73-8.
- [2]. Plass H, et al. Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jun;371(6):492-9.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 380 mg/kg TOXIC EFFECTS : Cardiac - other changes REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,156,1982
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