Tributyl phosphate 磷酸三丁酯

CAS 126-73-8 MFCD00009436

化学结构图

126-73-8
SMILES: CCCCOP(=O)(OCCCC)OCCCC

化学属性

Mol. Formula(CH3(CH2)3O)3PO
Mol. Weight266
Density0.979
Refractive indexn20/D 1.424(lit.)
Boiling Point180-183
Melting Point-79
Flash Point152°(305°F)
TSCAYes
Autoignition Point770 °F
Vapor Density9.2 (vs air)
Vapor Pressure27 mmHg ( 178 °C)
Solubility0.6 G/100 ML
Stability对湿度敏感

别名和识别编码

Chemical NameTributyl phosphate
Synonym ANTIFOAM T AURORA KA-1641 BUTYL PHOSPHATE Butyl phosphate ((BuO)3PO) Butyl phosphate, ((BuO)3PO) Butyl phosphate, tri- Celluphos 4 Disflamoll TB Kronitex TBP MCS 2495 N-BUTYL PHOSPHATE N-BUTYL-O-PHOSPHORIC ACID N-TRIBUTYL PHOSPHATE PHOSPHORIC ACID TRI-N-BUTYL ESTER PHOSPHORIC ACID TRIBUTYL ESTER Phosphoric acid tri-n-butyl ester Phosphoric acid, tributyl ester Phosphorsäuretri-n-butylester Phosphorsäuretributylester TBP TBP TBPA TBP TBPA 磷酸三丁酯 TBPA TRI-N-BUTYL ORTHOPHOSPHATE TRI-N-BUTYL PHOSPHATE TRIBUTYL PHOSPHATE Tri-n-butyl phosphate Tri-n-butylphosphat Tribut
CAS Number126-73-8
EC Number204-800-2
Beilstein Registry Number1710584
MDL NumberMFCD00009436
PubChem Substance ID24849766
Merck Number14,9618
Chemical Name Translation磷酸三丁酯
Wiswesser Line Notation4OPO&O4&O4
LabNetwork Molecule IDLN00197677
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分类

  • {SA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Organic Phosphates/
  • Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography,
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Standards for Personal Care and Cosmetic Products, T, TP - TZ, neats, prohibited substances (EU-REGULATION No 1223/2009)
  • {SNA} Ion Sensor Materials, Plasticizer for ISE, 分析/色谱
  • {SNA} Analytical/Chromatography, Ion Sensor Materials, Plasticizer for ISE
  • {SNA} Analytical Standards, Food and Cosmetic Component Standards, Organ
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Building Blocks, Chemical Synthesis, Organic Building Blo

产品应用

  • 硝化纤维及乙酸纤维素溶剂,消泡剂、热交换介质、增塑剂、萃取剂。气相色谱固定液(最高使用温度120℃,溶剂为乙醚)萃取钴、铱、锰、钼、钯、铑、镍、铀和钨,比色测定钼。有机合成。

相关文献及参考

  • Merck 14 ,9619
  • Beil. 1 ,IV,1531
  • Aldrich MSDS 1 , 1730:B / Corp MSDS 1 (2), 3398:B / FT-IR 1 (1), 926:B / FT-IR 2 (1), 1578:B / FT-NMR 1 (1), 1496:C / IR-Spectra (2), 493:C / IR-Spectra (3), 556:D / NMR-Reference 2 (2), 876:C / RegBook 1 (1), 1115:K / Sax 6 , 2612 / Structure Index 1 , 172:C:9
  • Short: III/35A Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Boron-11 and Phosphorus-31 Author: Gupta, R.R.; Jain, M.; Pardasani, P.; Pardasani, R.T.; Pelter, A. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35A Year: 1997 ISBN: 3-540-60366-2 ISBN: 978-3-540-60366-5 Internet Resource: DOI:10.1007/b53033 RefComment: VIII, 242 pages. With CD-ROM. Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1 (subvol. C), and carbon-13 (subvol. D) compounds are tabulated together with the gross- and structure formulas and the most readily available solvents. Due to the large amount of the data merely chemical shifts are presented in the printed versions, and all the data, chemical shifts and coupling constants are provided on CO-ROM's.
  • Short: III/38A Title: Refractive Indices of Inorganic, Organometallic, and Organononmetallic Liquids and Binary Liquid Mixtures Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38A Year: 1996 Keyword: organicmetallic compounds; inorganic compounds; refractive index; liquids; mixtures ISBN: 3-540-60539-8 ISBN: 978-3-540-60539-3 Internet Resource: DOI:10.1007/b55612 RefComment: VII, 400 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices

安全信息

GHS Symbol
WGK Germany2
Hazard Codes Xn Xn,F
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H302+H332
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTC7700000
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
Signal word Warning
Risk Statements
  • R11 Highly flammable 非常易燃
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R38 Irritating to skin 刺激皮肤
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R48/20
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Storage condition 密封保存。
UN Number UN 1208 3/PG 2
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 263 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 36(1,pt2),174,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 229 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 36(1,pt2),174,1997

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1189 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publish

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28 gm/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: FYI-OTS-0285-0380

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 24510 mg/m3/5H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   EDWU** "Beitrag zur Toxikologie Technischer Weichmachungsmittel,
   Dissertation," Eller, H., Pharmakologischen Institut der Universitat
   Wurzburg, Fed. Rep. Ger., 1937  Volume(issue)/page/year: -,-,1937

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 251 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publis

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 51(9),81,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 7500 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0491-1007S

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 43770 mg/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   40,90,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2750 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   32,1031,1994

其他信息

  • 灭火剂:二氧化碳、化学干粉、酒精泡沫、水雾
  • 毒性分级:中毒
  • 常规方法:玻璃瓶包装,外用木箱保护。贮于阴凉通风处。按有毒化学品规定贮运。
  • 用途二:对丙烯酸酯类、甲基丙烯酸酯类、丙烯酸、丙烯腈、苯乙烯、丁二烯有较好的阻聚效果,其阻聚性能优于酚类
  • 蒸气压:27 mm Hg ( 178 °C)
  • 防护措施:毒性低于磷酸三乙酯。大鼠经口LD50为3.0g/kg。大剂量经口能引起衰弱,呼吸困难,肺水肿,颤搐。对眼、皮肤、粘膜有刺激性。操作场所最高容许浓度为5mg/m3。应加强设备密闭。穿戴防护装具。
  • 用途四:用作硝酸纤维素、乙酸纤维素、氯化橡胶和聚氯乙烯的主增塑剂,也常用作涂料、粘合剂和油墨的溶剂、消泡剂、消静电剂,稀土元素的萃取剂。大鼠LD50为3000mg/kg。
  • 外观性质:无色、无味粘稠液体。
  • Sigma Aldrich:126-73-8(sigmaaldrich)
  • 方法一:由正丁醇与三氯氧磷反应而得。原料消耗(kg/t)丁醇 1500三氯氧磷 770
  • 用途一:用作气相色谱固定液、硝化纤维和乙基纤维素的溶剂、增塑剂、稀土金属分离用剂及有机合成中间体
  • 海关编码:29190010
  • 上游原料:三氯氧磷 --> 正丁醇 --> 三氯化磷
  • 类别:有毒物质
  • MSDS 信息:磷酸三丁酯(126-73-8).msds
  • 蒸气密度:9.2 (vs air)
  • 用途三:用作金属络合物的萃取剂,硝酸纤维素、醋酸纤维素、氯化橡胶和聚氯乙烯的增塑剂,涂料、油墨和粘合剂的溶剂
  • 可燃性危险特性:可燃; 火场中释放有毒磷氧化物烟雾
  • 无气味,能与多数有机溶剂混和,微溶于水(1ml溶于约165ml水)。低毒。
  • 储运特性:库房低温, 通风, 干燥
  • 刺激数据:皮肤-兔 10 毫克/24小时; 眼睛-兔 500 毫克 重度
  • Alfa Aesar:磷酸三正丁酯,98% Tri-n-butyl phosphate, 98%(126-73-8)
  • Acros Organics:三丁基磷酸酯 Tributyl phosphate, 99+%(126-73-8)
  • MOL 文件:126-73-8.mol
  • 用途五:硝化纤维及乙酸纤维素溶剂,消泡剂、热交换介质、增塑剂、萃取剂。气相色谱固定液(最高使用温度120℃,溶剂为乙醚)萃取钴、铱、锰、钼、钯、铑、镍、铀和钨,比色测定钼。有机合成。
  • 下游产品:直接蓝 86 --> 碳酸铈 --> 内墙涂料 --> 皮革涂饰剂
  • 磷酸三丁酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 10023018 磷酸三正丁酯;磷酸正丁酯;磷酸三正丁酯;三丁基磷酸盐;磷酸三丁脂 500ml 45元 2011/08/23 10023028 磷酸三正丁酯;磷酸正丁酯;磷酸三正丁酯;三丁基磷酸盐;磷酸三丁脂 500ml 43元 2011/08/23 xp400124 磷酸三丁酯;磷酸正丁酯;磷酸三正丁酯 5ml 45元
  • 急性毒性:口服-大鼠 LD50: 3000 毫克/公斤; 口服-小鼠 LD50: 1189 毫克/公斤
  • 职业标准:TWA 5 mg/m3;STEL 5 mg/m3

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