3-((chloro(diisopropylamino)phosphaneyl)oxy)propanenitrile 3-((chloro(diisopropylamino)phosphaneyl)oxy)propanenitrile
CAS 89992-70-1 MFCD00011544
化学结构图
SMILES: CC(C)N(C(C)C)P(Cl)OCCC#N
化学属性
| Mol. Formula | C9H18ClN2OP |
|---|---|
| Mol. Weight | 237 |
| Density | 1.061 |
| Refractive index | 1.4780 |
| Flash Point | >110°(230°F) |
| TSCA | No |
| Boiling Point | 103-105 |
| Stability | 易吸湿 |
别名和识别编码
| Chemical Name | 3-((chloro(diisopropylamino)phosphaneyl)oxy)propanenitrile |
|---|---|
| CAS Number | 89992-70-1 |
| Synonym | CYANOETHYL N,N-DIISOPROPYL PHOSPHOAMIDOCHLORIDITE 3-(Diisopropylaminochlorophosphinooxy)propiononitrile 氯代(二异丙基氨基)-β-氰基乙氧基膦 Phosphoramidochloridous acid, bis(1-methylethyl)-, 2-cyanoethyl ester Chloro(2-cyanoethoxy)(diisopropylamino)phosphine 2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 氯代(二异丙基氨基)-β-氰基乙氧基膦 3-[Chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile 2-氰乙基 N,N-二异丙基氯代亚磷酰胺 chloro(diisopropylamino)-β-cyanoethoxyphosphine N,N-Diisopropylamidochloridophosphorous acid 2-cyanoethyl ester 2-CYANOETHYL DIISOPROPYLCHLOROPHOSPHORAMIDITE, 14.0%-15.7% CL 2-CYANOETHYL DIISOPROPYLCHLOROPHOSPHORAMIDITE 3-(chloro(diisopropylamino)phosphinooxy)propanenitrile 2-氰基乙基二异丙基氯代亚磷酰胺 3-[Chloro(diisopropylamino)phosphinooxy]propiononitrile 2-氰乙基 N,N-二异丙基氯亚磷酰胺酯 2-CYANOETHYL DIISDPROPYLCHLOROPHOSPHORAMIDITE CHLORO(DIISOPROPYLAMINO)-BETA-CYANOETHOXYPHOSPHINE 氯代(二异丙基氨基)-β-氰基乙氧基膦;2-氰基乙基 二异丙基氯代亚磷酰胺 2-cyanoethyl-N,N-diisopropylchlorophosphoramidite 89992-70-4 Chloro(diisopropylamino)(2-cyanoethoxy)phosphine 2-Cyanoethoxy-N,N'-Diisopropyl Chlorophosphoramidate (2-Cyanoethoxy)(diisopropylamino)chlorophosphine 2-Cyanoethyl n,n-Diisopropylchlorophosphoramidite 2-氰乙基N,N-二异丙基氯亚磷酰胺 |
| PubChem Substance ID | 24858245 |
| Beilstein Registry Number | 3588525 |
| MDL Number | MFCD00011544 |
| Chemical Name Translation | 3-((chloro(diisopropylamino)phosphaneyl)oxy)propanenitrile |
| LabNetwork Molecule ID | LN00115985 |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SA} Building Blocks, Chemical Biology, Chemical Synthesis, Coupling Reagents, Nucleoside Chemistry, Organic Building Blocks, Phosphoramidites, Phosphorus Compounds
- Phosphorylating and Phosphitylating Agents
产品应用
- 用于可扩展性液相寡核苷酸合成，该合成用于亚磷酰胺化学和 DMT-、iBu- 以及 Bz-保护单体。中间体可通过萃取分离，无需进一步纯化。
- 用于寡脱氧核糖核苷酸合成过程中 3′-羟基的磷化试剂。
相关文献及参考
- Tetrahedron Lett., 24, 5843 (1983),
- 1. Tetrahedron Lett. 45 , 509, (2004)
- 2. Tetrahedron Lett. 35 , 5221, (1994)
- 3. Tetrahedron Lett. 34 , 6189, 6721, (1993)
- 4. Bioconjug. Chem. 4 , 499, (1993) 摘要
- Org. Process Res. Dev. 10 , 1238, (2006)
- Corp MSDS 1 (1), 936:D / FT-IR 2 (1), 1550:C / FT-NMR 1 (1), 1469:B / RegBook 1 (1), 1095:F / Structure Index 1 , 169:B:5
- Phosphitylating agent for use in oligonucleotide synthesis by the phosphite triester method: Tetrahedron Lett., 24, 5843 (1983); 27, 1211 (1986).
安全信息
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火
- P222 Do not allow contact with air. 不要与空气接触。
- P422 Store contents under… 存储目录在…之下。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P231 Handle under inert gas. 在惰性气体中操作。
- R5 Heating may cause an explosion 加热会引起爆炸
- R34 Causes burns 会导致灼伤
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R29 Contact with water liberates toxic gas. 遇水释放出有毒气体
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S8 Keep container dry 保持容器干燥；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
其他信息
- Alfa Aesar:2-氰基乙基二异丙基氯代亚磷酰胺,95% 2-Cyanoethyl diisopropylchlorophosphoramidite, 95%(89992-70-1)
- Sigma Aldrich:89992-70-1(sigmaaldrich)
- Acros Organics:2-氰乙基 N,N-二异丙基氯亚磷酰胺酯 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite, 97%(89992-70-1)
- F:10
- 2-氰乙基 N,N-二异丙基氯代亚磷酰胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 374830050 2-氰乙基 N,N-二异丙基氯代亚磷酰胺 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 97% 5 GR 3643元 2010/06/21 374830010 2-氰乙基 N,N-二异丙基氯代亚磷酰胺 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 97% 1 GR 1004元 2010/05/25 L18575 2-氰基乙基 二异丙基氯代亚磷酰胺, 95% 2-Cyanoethyl diisopropylchlorophosphoramidite, 95% 5g 2548元
- MSDS 信息:2-Cyanoethyl N,N-diisopropylchlorophosphoramidite(89992-70-1).msds
- 敏感性:Moisture Sensitive
- MOL 文件:89992-70-1.mol
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