(-)-Camphor (1S,4S)-1,7,7-三甲基双环[2.2.1]庚烷-2-酮

CAS 464-48-2 MFCD00064148

化学结构图

464-48-2
SMILES: CC1(C)[C@H]2CC[C@]1(C)C(=O)C2

化学属性

Mol. FormulaC10H16O
Mol. Weight152
Density5.24
Flash Point65°(149°F)
TSCAYes
Boiling Point204
Melting Point175.0 to 180.0 deg-C
Autoignition Point870 °F
Vapor Density5.24 (vs air)
Vapor Pressure4 mmHg ( 70 °C)
Refractive index-44 ° (C=20, EtOH)

别名和识别编码

Chemical Name(1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
Synonym L-2-Bornanone (1s,4s)-(-)-campho L-(-)-樟脑 l-Camphor 2-Camphanone (1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one 1,7,7-trimethylnorcamphor CAMPHOR, -(1S)-(-)- Caladryl (1S)-(-)-CAMPHOR L-(-)-CAMPHOR 1,7,7-三甲基二环[2.2.1]庚烷-2-酮 L-(-)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE 卡氟 (1S)​-​1,7,7-​Trimethylbicyclo[2.2.1]​heptan-​2-​one (1S)-CAMPHOR radian b 左旋樟脑 1-(-)CAMPHOR L-(-)-2-KETO-1,7,7-TRIMETHYLNORCAMPHANONE Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-, (1S)- (-)-CAMPHOR (-)-Alcanfor (-)-樟脑 (1S)-1,7,7-三甲基二环[2.2.1]庚烷-2-酮 l-(-)-Camphor L(-)-樟脑
CAS Number464-48-2
PubChem Substance ID444294
EC Number207-354-7
Beilstein Registry Number7(4)213
MDL NumberMFCD00064148
Reaxys-RN2500713
Merck Number1732
Chemical Name Translation(1S,4S)-1,7,7-三甲基双环[2.2.1]庚烷-2-酮
Wiswesser Line NotationL55 A CVTJ A1 A1 B1
LabNetwork Molecule IDLN00241903
InChIInChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, C, CA - CG, Chemical Class, Chromatography, Ketones, Life Sciences Standards, Natural Compounds, Nat
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Ketones, Organic Building Blocks
  • {SNA} Additional Standards, Analytical Standards, Chemical Class, Chromatography, Ketones, Life Sciences Standards, Natural Compounds, Natural Terpene Standards, 分析/色谱
  • {SNA} Additional Standards, Analytical Standards,

产品应用

  • 手性中间体,用于合成高效的增香剂、脱硫剂。

相关文献及参考

  • Merck: 14,1732
  • Merck: 14,1732 Beilstein:7(4)213

安全信息

GHS Symbol
WGK Germany1
Hazard Codes
Hazard statements
  • H228 Flammable solid 易燃固体
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSEX1250000
Precautionary statements
  • P203
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P370+P378
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word {} {} {} {} {} {} {} {} {TCI}
UN Number 2717 UN 2717 4.1/PG 3 UN2717
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
Risk Statements
  • R11 Highly flammable 非常易燃
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Packing GroupIII
Hazard Class4.1
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 1,445,1909

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02534

其他信息

  • 爆炸物危险特性:蒸汽遇高温, 明火, 氧化剂可爆炸
  • 储运特性:库房低温通风干燥; 与食品原料, 氧化剂分开存放; 防明火, 高温
  • 蒸气压:4 mm Hg ( 70 °C)
  • Sigma Aldrich:464-48-2(sigmaaldrich)
  • 可燃性危险特性:遇高温, 明火, 氧化剂易燃; 热分解辛辣刺激烟雾
  • TCI Shanghai:樟脑 (-)-Camphor,>;96.0%(GC)(464-48-2)
  • 灭火剂:水雾, 二氧化碳, 泡沫, 干粉
  • MOL 文件:464-48-2.mol
  • 急性毒性:口服-大鼠 LDL0: 0.8 毫克/公斤; 腹腔-小鼠 LD50: 320 毫克/公斤
  • 左旋樟脑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1251 (-)-樟脑 (-)-Camphor 5G 390元 2010/06/21 108190500 左旋樟脑 L(-)-Camphor , tech. 50 GR 3720元 2010/06/21 108190100 左旋樟脑 L(-)-Camphor , tech. 10 GR 942元
  • 蒸气密度:5.24 (vs air)
  • Acros Organics:L(-)-樟脑 L(-)-Camphor, tech.(464-48-2)
  • 用途一:手性中间体,用于合成高效的增香剂、脱硫剂。
  • Alfa Aesar:(1S)-(-)-樟脑,99% (1S)-(-)-Camphor, 99%(464-48-2)
  • 类别:易燃固体
  • 毒性分级:剧毒

系列性分类


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