Dibutyl phthalate 邻苯二甲酸二正丁酯

CAS 84-74-2 MFCD00009441

化学结构图

84-74-2
SMILES: CCCCOC(=O)c1ccccc1C(=O)OCCCC

化学属性

Mol. FormulaC16H22O4
Mol. Weight278
Refractive index1.4900 to 1.4950
Boiling Point340
Density1.043
Melting Point-35
Flash Point157°C
SolubilityVery soluble in alcohol, ether, acetone, benzene
TSCAYes
Autoignition Point756 °F
Vapor Density9.6 (vs air)
Vapor Pressure1 mmHg ( 147 °C)
Stability对湿度敏感

别名和识别编码

Chemical NameDibutyl phthalate
Synonym 1,2-苯二甲酸二丁酯;邻苯二甲酸二正丁酯;邻酞酸二丁酯;正丁基邻苯二甲酸酯;邻苯二甲酸二丁基酯;DBP Benzene-1,2-dicarboxylic acid di-n-butylester Celluflex DPB DBP;邻酞酸二丁酯 Di-n-butylester kyseliny ftalove Elaol PX 104 Phthalic acid dibutyl ester Polycizer DBP Witcizer 300 o-Benzenedicarboxylic acid, dibutyl ester 邻苯二甲酸二丁酯 邻苯二甲酸二丁酯标准溶液 邻苯二甲酸二正丁酯 邻苯二甲酸二正丁酯, 99%
CAS Number84-74-2
PubChem Substance ID87574526
EC Number201-557-4
Beilstein Registry Number1914064
MDL NumberMFCD00009441
Reaxys-RN1914064
Merck Number3035
Chemical Name Translation邻苯二甲酸二正丁酯
Wiswesser Line Notation4OVR BVO2
LabNetwork Molecule IDLN00195958
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分类

  • {SNA} Analytical Standards,
  • {SNA} Analytical Reagents, Analytical/Chromatography, Ion Sensor Materials, Microscopy Reagents, Plasticizer for ISE, Various Chemicals
  • {SNA} Acids and Esters, Additional Standards, Analytical Standards, Certified Reference Materials (CRMs), Fluka CRMs for Chromatography (neats), Food & Beverage Standards, Food Residuals, Food and Cosmetic Component Standards, Organic CRMs Alphabetical, Organic CRMs TraceCERT, Phthalates, Plasticizer, Processing & Packaging Contaminant Standards, SVHC, Standards for Personal Care and Cosmetic Products, prohibited substances (EU-REGULATION No 1223/2009), 分析/色谱
  • {SNA} Aloe Vera,
  • {SNA} Alo

产品应用

  • 有机合成,离子选择电极助剂,溶剂,杀虫剂,增塑剂,气相色谱固定液(最高使用温度100℃,溶剂为丙酮、苯、二氯甲烷、乙醇),选择性保留和分离芳族化合物、不饱和化合物、萜烯化合物以及各种含氧化合物(醇、醛、酮、酯等)。

相关文献及参考

  • Merck: 14,3035
  • Merck: 14,3035 Beilstein:9(2)586

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 9 T,N
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H303 May be harmfully swallowed 吞食可能有害
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H316 Causes mild skin irritation 会轻微的刺激皮肤
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTI0875000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P333+P313+P362+P364
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P308+P313
  • P337+P313
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 2810/9095/3082 3082 UN3082
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50 Very toxic to aquatic organisms 对水生生物极毒
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Packing GroupIII
Storage condition 冷藏(4℃)和避光下保存 密封保存。 储存温度2-8℃
Hazard Class9
TYPE OF TEST            : LC50 - Lethal concentration,

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C101,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9410 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(6),86,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - withdrawal
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 24(3),25,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSA

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 30 mg/L/24H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,337,1977

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 16,61,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2250 mg/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 86,163,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2520 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   26,253,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 305 mg/kg
SEX/DURATION            : female 5-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 61,51,1972

TYPE OF TEST

其他信息

  • 易溶于醇、醚、丙酮和苯,几乎不溶于水。对眼睛、呼呼系统、皮肤有刺激性
  • 易溶于醇、醚、丙酮和苯,几乎不溶于水。对眼睛、呼呼系统、皮肤有刺激性。

系列性分类


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