Tritolyl phosphate 磷酸三甲酚酯

CAS 1330-78-5 MFCD02102116

化学结构图

1330-78-5
SMILES: Cc1ccc(OP(=O)(Oc2ccc(C)cc2)Oc2ccc(C)cc2)cc1.Cc1cccc(OP(=O)(Oc2cccc(C)c2)Oc2cccc(C)c2)c1.Cc1ccccc1OP(=O)(Oc1ccccc1C)Oc1ccccc1C

化学属性

Mol. FormulaC₂₁H₂₁O₄P
Mol. Weight368.36
Refractive index1.5550 to 1.5580
Boiling Point-
Density1.16
TSCAYes
Flash Point-
Solubility不溶
Autoignition Point770 °F
Vapor Pressure0.03 mmHg ( 25 °C)
Melting Point<-40°C

别名和识别编码

Chemical NameTritolyl phosphate
Synonym Celluflex 179C Disflamoll TKP Durad Imol S 140 Lindol PHOSPHORIC AC PHOSPHORIC ACID TRITOLYL EST Phosflex 179A Phosphorsäuretris(methylphenyl)ester Isomerengemisch Sumiguard TBT Tricresyl Phosphate (Mixture of Isomers: o-cresol, m-cresol, p-cresol) {} {} {} {} {} {} { {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} tricresyl phosphate {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} tricresilfosfati {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} phosphat {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} nci-c61041 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {
CAS Number1330-78-5
PubChem Substance ID87574512
EC Number215-548-8
MDL Number-
Merck Number9763
Beilstein Registry Number2384789
Chemical Name Translation磷酸三甲酚酯
Wiswesser Line Notation1R XOPO&OR X1&OR X1
LabNetwork Molecule IDLN02135214
Canonical SMILES-
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分类

  • Building Blocks, Chemical Synthesis, Organic Building Blocks, Organic Phosphates/Phosphites, Phosphorus Compounds
  • {uni_hamburg} no charge; mineral; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment

产品应用

  • 用作环氧树脂胶粘剂的增塑剂,具有阻燃性能。

相关文献及参考

  • Merck: 14,9763
  • Short: IV/15A
  • Short: IV/6

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 6.1 T,N Xn,N,T
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P308+P311
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
RTECSTD0175000
UN Number 2574 3082 UN 2574 6.1/PG 2 UN2574 UN2810
Safety Statements
  • S20/21 When using do not eat, drink or smoke 使用时,不得进食,饮水或吸烟;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R50/53
  • R51/53
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
Packing GroupII
Storage condition 4°C, Hygroscopic 贮存于阴凉、通风的库房内。
Hazard Class9
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,585,1957

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 70 mg/kg/14D
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 1,88,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(i

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,114,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2250 mg/kg
SEX/DURATION            : male 7 day(s) pre-mating
                          female 7 day(s) pre-mating  - 22 day(s) after
                          conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - germ cell effects (in offspring)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   10,344,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4550 mg/kg
SEX/DURATION            : male 13 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 6,292,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7250 mg/kg
SEX/DURATION            : female 7 day(s) pre-mating
                          female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - live birth index (measured after birth)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   10,344,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1750 mg/kg
SEX/DUR

其他信息

  • 灭火剂:水、泡沫、砂土、二氧化碳
  • 毒性分级:中毒
  • 刺激数据:皮肤- 兔子 500 毫克 轻度; 眼- 兔子 500毫克/ 24小时 轻度
  • 上游原料:三氯氧磷 --> 氯 --> 二甲酚
  • 职业标准:TLV-TWA 0.1 毫克/ 立方米
  • 类别:有毒物品
  • 无色或浅黄色油状液体,略带苯酚气味。工业品为三种异构体的混合物,通常尽可能除去毒性很大的邻位异构体,粘度(20 ℃)78~185mPa·s。溶于苯、醚类、醇类、油类。不溶于水,易燃、剧毒。
  • 急性毒性:口服- 大鼠 LD50: 5190 毫克/ 公斤; 口服- 小鼠 LD50: 3900 毫克/ 公斤
  • 图谱信息:磷酸三甲苯酯(1330-78-5)红外图谱(IR1) 磷酸三甲苯酯(1330-78-5)质谱(MS) 磷酸三甲苯酯(1330-78-5)红外图谱(IR2)
  • 下游产品:邻磷酸三甲酚酯
  • 用途一:用作分析试剂、硝化纤维的溶剂及增塑剂
  • Alfa Aesar:<1% Tritolyl phosphate, mixture of isomers, 98%, ortho-isomers <1%(1330-78-5)" href="http://www.alfa.com/zh/GP100w.pgm?DSSTK=A17433&CAS;=1330-78-5">磷酸三甲苯酯,异构体混合物,98%,ortho-isomers<1% Tritolyl phosphate, mixture of isomers, 98%, ortho-isomers <1%(1330-78-5)
  • 蒸气压:0.03 mm Hg ( 25 °C)
  • TCI Shanghai:磷酸三甲苯酯(异构体的混合物) Tricresyl Phosphate (mixture of isomers),>;99.0%(GC)(1330-78-5)
  • Acros Organics:磷酸三甲苯酯,异构体混合物 Tritolyl phosphate, mixture of isomers, 99%(1330-78-5)
  • 化学特性:磷酸三甲苯酯(1330-78-5)为异构体混合物,无色或微黄色透明油状液体。略带苯酚气味,稳定不挥发,具有良好的阻燃性、耐油性、电绝缘性、易加工性,不溶于水,与所有通用的有机溶剂混溶。工业品为三种异构体的混合物,通常尽可能除去毒性很大的邻位异构体。
  • 磷酸三甲苯酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80134028 磷酸三甲酚酯 500ml 58元 2011/08/23 40059560 磷酸三甲酚酯 100g 14.2元 2011/04/16 P0273 磷酸三甲苯酯(异构体的混和物) Tricresyl Phosphate (mixture of isomers) 25G 124元
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂分开存放
  • 外观性质:无色或淡黄色的透明油状液体。
  • 用途三:用作环氧树脂胶粘剂的增塑剂,具有阻燃性能。
  • MOL 文件:1330-78-5.mol
  • Sigma Aldrich:1330-78-5(sigmaaldrich)
  • 可燃性危险特性:遇明火、高热可燃; 燃烧时放出有毒的磷氧化物气体
  • 用途二:磷酸三甲苯酯是生产乙烯基树脂、硝化纤维素、聚氯乙烯、电缆橡胶制品及软质聚氨酯泡沫塑料等的重要的增塑.阻燃型添加剂, 与高聚物有良好的耐磨性、耐侯性、防霉性耐辐射性及电性能:还是一种调治机齿轮油、润滑油的重要极压抗磨剂。
  • MSDS 信息:磷酸三甲苯酯(1330-78-5).msds

系列性分类


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