N,N-Dimethyl-4-nitrosoaniline N,N-二甲基-4-亚硝基苯胺

CAS 138-89-6 MFCD00002063

化学结构图

138-89-6
SMILES: CN(C)c1ccc(N=O)cc1

化学属性

Mol. FormulaC₈H₁₀N₂O
Mol. Weight150.2
Melting Point85-86°C
Density1.15
TSCAYes
Solubility不溶于水,溶于乙醇、乙醚。
Boiling Point

别名和识别编码

Chemical NameN,N-Dimethyl-4-nitrosoaniline
Synonym 1-(Dimethylamino)-4-nitrosobenzene 4-(Dimethylamino)nitrosobenzene 4-NITROSO-N,N-DIMETHYLANILINE 4-Nitroso 4-Nitroso-N,N-dimethylaniline 4-Nitrosodimethylanilin 4-Nitrosodimethylaniline p-(Dimethylamino)nitrosobenzene p-(N,N-Dimethylamino)nitrosobenzene p-Nitrosodimethylanilide p-Nitrosodimethylanilin Accelerene Accelerine Aniline Aniline, N,N-dimethyl Benzenamine, N,N-dimethyl-4-nitroso- Benzenamine,N,N-dimethyl-4-nitroso- Dimethyl(p-nitrosophenyl)amine Dimethyl(p-nitrosophenyl)amine Dimethyl-(4-nitroso-phenyl)-amine Dimethyl-p-nitrosoaniline N,N N,N-DIMETHY N,N-DIMETHYL-4-NITROSOANILINE p-(D
MDL NumberMFCD00002063
CAS Number138-89-6
PubChem Substance ID8749
Beilstein Registry Number607293
EC Number205-343-1
Merck Number6638
Chemical Name TranslationN,N-二甲基-4-亚硝基苯胺
Reaxys-RN607293
Wiswesser Line NotationONR DN1&1
LabNetwork Molecule IDLN01102746
InChIInChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3
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分类

  • {SNA} D, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学, 血液学和组织学
  • {SNA} D, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment

相关文献及参考

  • Short: II/3
  • {
  • Short: II/27B
  • Similarly, converts benzylpyridinium salts to aldehydes (Krohnke reaction): Org. Synth. Coll., 5, 825 (1973).
  • Reagent for the conversion of toluenes with activated methyl groups to aldehydes, by condensation and subsequent hydrolysis of the imine: Org. Synth. Coll., 2, 223 (1943):

安全信息

RTECSBX7175000
GHS Symbol
Precautionary statements
  • P235+P410
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P312+P330
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P407 Maintain air gap between stacks/pallets. 在堆叠/货板间保持气隙。
  • P420 Store away from other materials. 远离其他材料。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301 Toxic if swallowed 吞食有毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H251 Self-heating: may catch fire 自我放热:可能着火
WGK Germany3
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Danger
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Packing GroupII
UN Number 1369 UN1369
Risk Statements
  • R11 Highly flammable 非常易燃
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R33 Danger of cumulative effects 有累积作用的危险
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
Hazard Codes 4.2 F,T
Hazard Class4.2
Storage condition -20 Flammables area
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7300 mg/kg/1Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   PUOMA5 Proceedings of the University of Otago Medical School.  (Otago
   Medical School Research Soc., Box 913, Dunedin, New Zealand)  V.1-    1922-
   Volume(issue)/page/year: 46,68,1968

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   JIDHAN Journal of Industrial Hygiene.  (Cambridge, MA)  V.1-17, 1919-35. For
   publisher information, see AEHLAU.  Volume(issue)/page/year: 13,87,1931

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8(Suppl
   7),1,1986

Restrict 危险品

其他信息

  • 灭火剂:水、泡沫、砂土、二氧化碳
  • Acros Organics:N,N-二甲基-4-亚硝基苯胺 N,N-Dimethyl-4-nitrosoaniline, 99%(138-89-6)
  • 用途一:测定二氧化碳时用以吸收氯化氢,苯基葡萄糖的沉淀剂,测定氯化氢、钯和高氯酸盐,分光光度测定铱、钯、铂和铑。
  • 毒性分级:中毒
  • MSDS 信息:N,N-二甲基对亚硝基苯胺(138-89-6).msds
  • 外观性质:绿色片状固体。
  • MOL 文件:138-89-6.mol
  • 可燃性危险特性:可燃; 遇热分解放出有毒苯胺和氮氧化物和氯化氢气体
  • 急性毒性:口服-大鼠 LD50:650 毫克/公斤
  • N,N-二甲基-4-亚硝基苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 N0262 N,N-二甲基-4-亚硝基苯胺 N,N-Dimethyl-4-nitrosoaniline 500G 3830元 2014/06/02 N0262 N,N-二甲基-4-亚硝基苯胺 N,N-Dimethyl-4-nitrosoaniline 25G 396元 2010/06/21 116491000 N,N-二甲基-4-亚硝基苯胺 N,N-Dimethyl-4-nitrosoaniline 99% 100 GR 908元
  • Sigma Aldrich:138-89-6(sigmaaldrich)
  • 图谱信息:N,N-二甲基-4-亚硝基苯胺(138-89-6)质谱(MS) N,N-二甲基-4-亚硝基苯胺(138-89-6)核磁图( 13 CNMR) N,N-二甲基-4-亚硝基苯胺(138-89-6)红外图谱(IR1) N,N-二甲基-4-亚硝基苯胺(138-89-6)红外图谱(IR2) N,N-二甲基-4-亚硝基苯胺(138-89-6)核磁图( 1 HNMR)
  • F:4.7-8-9
  • TCI Shanghai:N,N-二甲基-4-亚硝基苯胺 N,N-Dimethyl-4-nitrosoaniline,>;98.0%(GC)(T)(138-89-6)
  • 类别:自燃物品
  • 下游产品:乙基香兰素 --> 2,4-二硝基苯甲醛 --> 花菁
  • 储运特性:库房通风低温干燥; 与酸分开存放
  • Alfa Aesar:N,N-二甲基-4-亚硝基苯胺,97% N,N-Dimethyl-4-nitrosoaniline, 98%(138-89-6)
  • 方法一:将30g二甲基苯胺溶于100ml浓盐酸,在冰盐浴中冷却,搅拌下缓缓滴加含18g亚硝酸钠的50ml水溶液,保持反应液温度为0-5℃。加毕,继续搅拌半小时。吸滤,滤饼用水洗涤,真空干燥,得成品。

系列性分类


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