1-(2-Chloroethyl)piperidine hydrochloride N-(2-氯乙基)哌啶盐酸盐

CAS 2008-75-5 MFCD00012837

化学结构图

2008-75-5
SMILES: Cl.ClCCN1CCCCC1

化学属性

Mol. FormulaC7H15Cl2N
Mol. Weight184.11
Density1.422
Melting Point230-232°C
TSCANo
Solubility可溶
Appearance 白色或类白色结晶粉末,熔点 228-234 ℃ 。水溶性 soluble
Boiling Point196 °C at 760 mmHg

别名和识别编码

Chemical NameN-(β-Chloroethyl)piperidine Hydrochloride
CAS Number2008-75-5
Alfabeta NameCHLOROETHYLPIPERIDINEHYDROCHLORIDE 12()--
MDL NumberMFCD00012837
EC Number217-920-5
Beilstein Registry Number3910268
Synonym 2-Piperidinoethyl chloride hydrochloride {LY} 2-Piperidinoethyl chloride hydrochloride {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Piperidinoethyl chloride hydrochloride {} {} {} {} {}
PubChem Substance ID74826
Reaxys-RN3675792
Chemical Name TranslationN-(2-氯乙基)哌啶盐酸盐
Wiswesser Line NotationT6NTJ A2G &GH
LabNetwork Molecule IDLN00173829
InChIKeyVFLQQZCRHPIGJU-UHFFFAOYSA-N
InChIInChI=1S/C7H14ClN.ClH/c8-4-7-9-5-2-1-3-6-9;/h1-7H2;1H
Canonical SMILESClCCN1CCCCC1.[H]Cl
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分类

  • {SNA} Building Blocks, C5 to C7, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Piperidines

相关文献及参考

  • Beilstein:20,17

安全信息

Warnings IRRITANT
Signal word Danger
GHS Symbol
WGK Germany2
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R28 Very toxic if swallowed 吞咽极毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P301+P310+P330
  • P301+P316
  • P301+P330+P331
  • P302+P361+P354
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P305 IF IN EYES: 如果进入眼睛
  • P305+P351+P338
  • P305+P354+P338
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P316
  • P318
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H300 Fatal if swallowed 吞食致命
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSTM6482500
Packing GroupII
UN Number 2928
Storage condition 2-8°C {LY} 2-8°C Hygroscopic Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}
Hazard Codes 6.1 T+ T+,Xi
Hazard Class6.1/8
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#07326

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,25,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 93 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 94,249,1948

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 44 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,33,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5400 nmol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 500 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5400 nmol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

其他信息

  • Sigma Aldrich:2008-75-5(sigmaaldrich)
  • 类别:有毒物质
  • Acros Organics:1-(2-氯乙基)哌啶盐酸盐 1-(2-Chloroethyl)piperidine hydrochloride, 98%(2008-75-5)
  • 毒性分级:中毒
  • 溶于水,溶于热乙醇和热丙酮,冷乙醇和冷丙酮差些,不溶于苯和甲苯。
  • 可燃性危险特性:可燃; 火场分解有毒氯化物,氮氧化物气体
  • TCI Shanghai:1-(2-氯乙基)哌啶盐酸盐 1-(2-Chloroethyl)piperidine Hydrochloride,>;98.0%(T)(2008-75-5)
  • 海关编码:29333999
  • MSDS 信息:1-(2-Chloroethyl)piperidine hydrochloride(2008-75-5).msds
  • 1-(2-氯乙基)哌啶盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1073 1-(2-氯乙基)哌啶盐酸盐 1-(2-Chloroethyl)piperidine Hydrochloride 500G 1120元 2014/06/02 C1073 1-(2-氯乙基)哌啶盐酸盐 1-(2-Chloroethyl)piperidine Hydrochloride 25G 202元 2010/06/21 109211000 1-(2-氯乙基)哌啶盐酸盐 1-(2-Chloroethyl)piperidine hydrochloride 98% 100 GR 466元
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • MOL 文件:2008-75-5.mol
  • 储运特性:库房低温, 通风, 干燥
  • 急性毒性:腹腔-小鼠 LD50: 93 毫克/公斤; 皮下-小鼠 LD50: 125 毫克/公斤
  • Alfa Aesar:1-(2-氯乙基)哌啶盐酸盐,98% 1-(2-Chloroethyl)piperidine hydrochloride, 98%(2008-75-5)
  • 图谱信息:1-(2-氯乙基)哌啶盐酸盐(2008-75-5)红外图谱(IR2) 1-(2-氯乙基)哌啶盐酸盐(2008-75-5)质谱(MS) 1-(2-氯乙基)哌啶盐酸盐(2008-75-5)红外图谱(IR1) 1-(2-氯乙基)哌啶盐酸盐(2008-75-5)核磁图( 1 HNMR) 1-(2-氯乙基)哌啶盐酸盐(2008-75-5)核磁图( 13 CNMR)
  • 敏感性:Hygroscopic

系列性分类


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