Ethylurea 乙基尿素

CAS 625-52-5 MFCD00007953

化学结构图

625-52-5
SMILES: CCNC(N)=O

化学属性

Mol. FormulaC3H8N2O
Mol. Weight88.11
Melting Point87-90 °C
TSCAYes
Density1.005
Solubility可溶
Flash Point93 °C
Appearance 乙基脲纯品为白色结晶,m.p.92℃,工业品为白色鳞片状固体,易吸潮,在水中溶解度很大。
Boiling Point163.08 °C at 760 mmHg

别名和识别编码

Chemical NameEthylurea
Beilstein Registry Number1740512
PubChem Substance ID12254
CAS Number625-52-5
EC Number210-898-8
MDL NumberMFCD00007953
Reaxys-RN1740512
Synonym 1-Ethylurea {LY} 1-Ethylurea {} {LY} 1-Ethylurea {} {} {LY} 1-Ethylurea {} {} {} {LY} 1-Ethylurea {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Ethylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Chemical Name Translation乙基尿素
Wiswesser Line NotationZVM2
LabNetwork Molecule IDLN00221723
InChIInChI=1S/C3H8N2O/c1-2-5-3(4)6/h2H2,1H3,(H3,4,5,6)
Canonical SMILESO=C(N)NCC
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分类

  • {Chemicalbook} 农药中间体: 杀菌剂中间体: 脂肪族类杀菌剂
  • Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks, Ureas
  • {SNA} Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks, Ureas
  • {uni_hamburg} no charge; urea; 1fragment

相关文献及参考

  • Short: II/27B
  • Short: III/35B
  • Beilstein:4,115

安全信息

RTECSYT2335000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R37 Irritating to respiratory system 刺激呼吸道
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Packing GroupIII
UN Number 1325
Hazard Codes Xn
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,47,1953

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6610 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 52,216,1934

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Protozoa - Chlamydomonas reinhardi
DOSE/DURATION           : 400 mmol/L
REFERENCE :
   FOMIAZ Folia Microbiologica (Prague).  (Academia, Vodickova 40, 112 29
   Prague 1, Czechoslavakia) V.4-    1959-  Volume(issue)/page/year:
   20,452,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 gm/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 23,335,1981

Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • N-乙基脲价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010263 乙基脲 100g 300元 2011/08/23 xw010264 乙基脲 25g 100元 2011/04/16 E0192 乙基脲 Ethylurea 500G 3340元
  • Acros Organics:乙基尿素 Ethylurea, 97%(625-52-5)
  • 用途二:乙基脲是杀菌剂霜脲氰的中间体。
  • MOL 文件:625-52-5.mol
  • 方法一:其制备方法是在反应釜中加入甲苯、尿素,加盖密封,搅拌加热到一定温度,随后通入定量的乙胺,通毕继续搅拌0.5h,冷至40~50℃,将物料放至结晶锅,继续冷至0~5℃,过滤,干燥,得白色鳞片状结晶为成品。
  • 图谱信息:N-乙基脲(625-52-5)红外图谱(IR1) N-乙基脲(625-52-5)核磁图( 1 HNMR) N-乙基脲(625-52-5)红外图谱(IR2) N-乙基脲(625-52-5)核磁图( 13 CNMR) N-乙基脲(625-52-5)质谱(MS)
  • TCI Shanghai:乙基脲 Ethylurea,>;95.0%(T)(625-52-5)
  • 用途一:用于医药、农药合成的中间体
  • MSDS 信息:N-Ethylurea(625-52-5).msds
  • Alfa Aesar:乙基尿素,98% Ethylurea, 98%(625-52-5)
  • Sigma Aldrich:625-52-5(sigmaaldrich)
  • 下游产品:霜脲氰 --> 洛莫司汀 --> 卡莫司汀 --> 1-氰乙酰基-3-乙基脲

系列性分类


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