STRYCHNINE NITRATE 马钱子碱硝酸盐

CAS 66-32-0 MFCD00078519

化学结构图

66-32-0
SMILES: [O-][N+](O)=O.O=C1C[C@@H]2OCC=C3CN4CC[C@@]56[C@@H]4C[C@@H]3[C@@H]2[C@@H]5N1C1C=CC=CC6=1 |&1:7,16,17,19,20,21|

化学属性

Mol. FormulaC21H22N2O2.HNO3
Mol. Weight397.47

别名和识别编码

Chemical NameStrychnine, mononitrate
MDL NumberMFCD00078519
EC Number200-627-1
CAS Number66-32-0
Synonym 硝酸士的宁 StrychnineHCL,(L-A046) strychnidin-10-one,mononitrate STRYCHNINE NITRATE: 98.5% strychnine,mononitrate 马钱子碱硝酸盐 Strychninenitrate,(L-A044) Strychnine nitrate 士的宁硝酸盐 Strychnidin-10-one, mononitrate 番木虌鹼硝酸鹽 STRYCHNINE NITRATE SALT STRYCHNINE NITRATE
Chemical Name Translation马钱子碱硝酸盐
Merck Number8855
Wiswesser Line NotationT6 G656 B7 C6 E5 D 5ABCEF A& FX MNV QO VN SUAHT&&TTTTJ
LabNetwork Molecule IDLN01746350
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分类

  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Complex Molecules

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H300 Fatal if swallowed 吞食致命
Signal word Danger
Packing GroupI
Hazard Codes T+
Hazard Class6.1(a)
UN Number UN 1692 6.1/PG 1
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
RTECSWL2450000
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒
Restrict 剧毒化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 207,688,1949

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,1778,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 930 ug

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255,

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   21,1,1958

TYP

其他信息

  • 毒性分级:剧毒
  • Sigma Aldrich:66-32-0(sigmaaldrich)
  • 类别:有毒物质
  • MOL 文件:66-32-0.mol
  • TCI Shanghai:硝酸马钱子碱 Strychnine Nitrate,>;98.5%(T)(66-32-0)
  • 图谱信息:马钱子碱硝酸盐(66-32-0)红外图谱(IR1) 马钱子碱硝酸盐(66-32-0)红外图谱(IR2) 马钱子碱硝酸盐(66-32-0)核磁图( 13 CNMR) 马钱子碱硝酸盐(66-32-0)核磁图( 1 HNMR)
  • 储运特性:库房低温, 通风, 干燥; 与食品原料分开存放
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • 急性毒性:口服- 大鼠 LD50 16.2 毫克/ 公斤; 口服- 小鼠 LD50: 0.93 毫克/公斤
  • 可燃性危险特性:可燃; 火场分解有毒氮氧化物烟雾

系列性分类


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