Acetylsalicylic anhydride 乙酰水杨酸酐

CAS 1466-82-6 MFCD00013236

化学结构图

1466-82-6
SMILES: CC(=O)Oc1ccccc1C(=O)OC(=O)c1ccccc1OC(C)=O

化学属性

Mol. FormulaC18H14O7
Mol. Weight342.30
Melting Point80-83°C
Boiling Point511.2°C at 760 mmHg

别名和识别编码

Chemical NameAcetylsalicylic Anhydride
CAS Number1466-82-6
Synonym 2-Acetoxybenzoic anhydride {LY} 2-Acetoxybenzoic anhydride {} {LY} 2-Acetoxybenzoic anhydride {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Acetoxybenzoic anhydride
MDL NumberMFCD00013236
PubChem Substance ID15110
Beilstein Registry Number2015320
EC Number215-987-5
Chemical Name Translation乙酰水杨酸酐
LabNetwork Molecule IDLN00338764
InChIInChI=1S/C18H14O7/c1-11(19)23-15-9-5-3-7-13(15)17(21)25-18(22)14-8-4-6-10-16(14)24-12(2)20/h3-10H,1-2H3
Canonical SMILESO=C(OC(C1=CC=CC=C1OC(C)=O)=O)C2=CC=CC=C2OC(C)=O
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分类

  • Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,,
  • {SNA} Building Blocks, Carbonyl Compounds, Carboxylic Acid Anhydrides, Chemical Synthesis, Organic Building Blocks

产品应用

  • Acetylsalicylic Acid Impurity D.

相关文献及参考

  • Dannan H., et al.: J. Pharm. Sci., 75, 1081 (1986),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSVO0710000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Cardiac - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,514,1960

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 300 mg/L
REFERENCE :
   GMCRDC Gann Monograph on Cancer Research.  (Plenum Pub. Corp., 233 Spring
   St., New York, NY 10013) No. 11-    1971-  Volume(issue)/page/year:
   27,95,1981

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

系列性分类


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