3-(O-Tolyloxy)Propane-1,2-Diol 3-(邻甲苯氧基)丙烷-1,2-二醇

CAS 59-47-2 MFCD00004718

化学结构图

59-47-2
SMILES: Cc1ccccc1OCC(O)CO

化学属性

Mol. FormulaC10H14O3
Mol. Weight182
Boiling Point154°C/4mmHg(lit.)
Melting Point69.0 to 73.0 deg-C
SolubilitySoluble in alcohol
TSCANo

别名和识别编码

Chemical Name3-(O-Tolyloxy)Propane-1,2-Diol
MDL NumberMFCD00004718
CAS Number59-47-2
Synonym 1,2-Dihydroxy-3-(2-methylphenoxy)propane 1-Ortho-tolylglycerol ether 3-(2-Methylphenoxy)-1,2-propanediol 3-(2-甲基苯氧基)-1,2-丙烷二醇, 98% 3-(o-Tolyloxy)propane-1,2-diol 3-o-Toloxy-1,2-propanediol A 1141 Ageflex CGE Atensin Avosyl Avoxyl BDH 312 BYK-M 1 Cresodiol Cresossidiolo Cresossipropandiolo Cresoxydiol Cresoxypropanediol Dioloxol Findolor Glykresin Glyotol Kinavosyl Lissephen Mefensina Memphenesin Mephedan Mephenesin Mephenesine Mephensin Mepherol Mephesin Myanesin Myanol Myastenin Mycocuran Myodetensine Myolysin Myopan Myoserol Myoten Myoxane Oranixon Prolax RP 3602 Relaxar Relaxil Renarcol Sinan Spartoloxyn Stilalgin Thoxidil Tolax Tolhart Toloxyn Tolserol Tolsin Tolulexin Tolulox Tolyspaz Torulox Walko-nesin Xeral alpha,beta-Dihydroxy-gamma-(2-methylphenoxy)propane alpha-(o-Tolyl)glyceryl ether o-Cresol glyceryl ether o-Cresyl alpha-glyceryl ether o-Kresol-glycerinaether
PubChem Substance ID4059
EC Number200-427-4
Merck Number14,5850
Chemical Name Translation3-(邻甲苯氧基)丙烷-1,2-二醇
Wiswesser Line NotationQ1YQ1OR B1
Beilstein Registry Number2047373
LabNetwork Molecule IDLN00196153
Reaxys-RN2047373
InChIInChI=1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds, Polyols

安全信息

WGK Germany2
GHS Symbol
Precautionary statements
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P305+P351+P338
  • P301+P312+P330
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSTZ1225000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36 Irritating to eyes 刺激眼睛
Hazard Codes Xn
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 283 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimo

{

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 133 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 85,323,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 821 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   IJNEAQ International Journal of Neuropharmacology.  (New York, NY)  V.1-8,
   1962-69.  For publisher information, see NEPHBW.  Volume(issue)/page/year:
   5,305,1966

TYPE OF TEST

系列性分类


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