Phthalazin-1(2H)-one 1-(2H)-酞嗪酮

CAS 119-39-1 MFCD00006892

化学结构图

119-39-1
SMILES: O=c1[nH]ncc2ccccc12

化学属性

Mol. FormulaC8H6N2O
Mol. Weight146.15
Density1.422
Melting Point183-185°C
Boiling Point423.4°C at 760 mmHg
Flash Point209.9°C

别名和识别编码

Chemical NamePhthalazin-1(2H)-one
CAS Number119-39-1
Alfabeta NamePHTHALAZINONE H12()-
MDL NumberMFCD00006892
EC Number204-319-8
Beilstein Registry Number3654
Synonym Phthalazin-1(2H)-one {LY} Phthalazin-1(2H)-one {} {LY} Phthalazin-1(2H)-one {} {} {LY} Phthalazin-1(2H)-one {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phthalazin-1(2H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID87575279
Chemical Name Translation1-(2H)-酞嗪酮
Reaxys-RN3654
Wiswesser Line NotationT66 BVMNJ
LabNetwork Molecule IDLN00159643
Canonical SMILESO=C1NN=CC2=C1C=CC=C2
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, Pyridazines

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard Codes Xn
Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSTH9185000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00139

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
   Series, Bulletin. (Pittsburgh, PA)  1947-69.  Volume(issue)/page/year:
   6,1,1967

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • MOL 文件:119-39-1.mol
  • MSDS 信息:Benzo[d]pyridazin-1(2H)one(119-39-1).msds
  • Sigma Aldrich:119-39-1(sigmaaldrich)
  • 下游产品:1-氯酞嗪
  • 1-(2H)-酞嗪酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P1179 2,3-二氮杂萘酮 Phthalazone 25G 263元 2014/06/02 P1179 2,3-二氮杂萘酮 Phthalazone 500G 1870元 2010/06/21 384570050 1-(2H)-酞嗪酮 1(2H)-Phthalazinone 98+% 5 GR 271元
  • 海关编码:29339990
  • 方法一:可用萘在碱性条件下以高锰酸钾氧化,生成-α-羧基苯乙酮酸,然后与硫酸肼环合得1-羟基酞嗪-4-羧酸,后者经高温脱羧(消除)制得该品。
  • 用途一:肼苯哒嗪盐酸盐的中间体。
  • TCI Shanghai:2,3-二氮杂萘酮 Phthalazone,>;98.0%(GC)(119-39-1)
  • 图谱信息:1-(2H)-酞嗪酮(119-39-1)核磁图( 1 HNMR) 1-(2H)-酞嗪酮(119-39-1)红外图谱(IR1) 1-(2H)-酞嗪酮(119-39-1)质谱(MS) 1-(2H)-酞嗪酮(119-39-1)红外图谱(IR2) 1-(2H)-酞嗪酮(119-39-1)核磁图( 13 CNMR)
  • Acros Organics:1(2H)-Phthalazinone, 98+%(119-39-1)
  • 上游原料:高锰酸钾 --> 硫酸肼 --> 苯甲酰甲酸

系列性分类


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