2-Hydroxyethylhydrazine 2-肼基乙醇

CAS 109-84-2 MFCD00007623

化学结构图

109-84-2
SMILES: NNCCO

化学属性

Mol. FormulaC2H8N2O
Mol. Weight76.10
Refractive index1.4860 to 1.4940
Boiling Point155-160°C at 760 mmHg
Density1.121
Melting Point-70°C
TSCAYes
Flash Point77°C
Solubility能与水混溶,溶于低级醇,微溶于醚。水溶液为碱性。
pH:A

别名和识别编码

Chemical Name2-Hydroxyethylhydrazine
CAS Number109-84-2
Alfabeta NameHYDRAZINOETHANOL 2-
MDL NumberMFCD00007623
Synonym 2-Hydrazinoethanol {LY} 2-Hydrazinoethanol {} {LY} 2-Hydrazinoethanol {} {} {LY} 2-Hydrazinoethanol {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Hydrazinoethanol {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID87570766
EC Number203-711-6
Beilstein Registry Number4(4)3348
Reaxys-RN1731669
Chemical Name Translation2-肼基乙醇
Merck Number13,4794
Wiswesser Line NotationZM2Q
LabNetwork Molecule IDLN00007612
InChIInChI=1S/C2H8N2O/c3-4-1-2-5/h4-5H,1-3H2
Canonical SMILESNNCCO
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分类

  • Building Blocks, Chemical Synthesis, Hydrazines, Nitrogen Compounds, Organic Building Blocks
  • {SNA} Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds

产品应用

  • 用作有机合成中间体、燃料油的稳定剂、植物生长调节剂。

相关文献及参考

  • Merck:13,4794 Beilstein: 4,IV,3348
  • Merck:13,4794

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H301+H311+H331
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes T
RTECSKL2800000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P310+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P501a
Signal word
UN Number 2810 UN2810
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R25 Toxic if swallowed 吞咽有毒
Packing GroupIII
Hazard Class6.1
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 572 mg/kg/78W-I-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   42,1101,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 139 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 2,76,1968

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1100 ug/plate
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 72,5135,1975

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 100 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 78,177,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 116,185,1983

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 5 pph
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,19,1976

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amste

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 pph
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,19,1976

{haza

Storage condition -20°C, stored under nitrogen {LY} -20°C, stored under nitrogen {} {LY} -20°C, stored under nitrogen {} {} {LY} -20°C, stored under nitrogen {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 方法一:由环氧乙烷与水合肼加成而得。40%的水合肼与环氧乙烷在65-75℃反应后,进行减压浓缩,即得2-羟乙基肼。有的反应实例将温度控制在40℃以下,收率为60-64%。
  • 图谱信息:2-肼基乙醇(109-84-2)Raman光谱 2-肼基乙醇(109-84-2)红外图谱(IR1)
  • Alfa Aesar:(2-羟乙基)肼 (2-Hydroxyethyl)hydrazine(109-84-2)
  • 外观:无色透明油状液体。
  • 2-肼基乙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010231 2-羟乙基肼 25g 250元 2011/04/16 H0350 2-肼基乙醇 2-Hydrazinoethanol 500G 3050元 2011/04/16 H0350 2-肼基乙醇 2-Hydrazinoethanol 25G 383元
  • 用途二:用作有机合成中间体、燃料油的稳定剂、植物生长调节剂。
  • MSDS 信息:2-Hydroxyethylhydrazine(109-84-2).msds
  • Hazard Note:Toxic
  • MOL 文件:109-84-2.mol
  • TCI Shanghai:2-肼基乙醇 2-Hydrazinoethanol,>;95.0%(T)(109-84-2)
  • 能与水混溶,溶于低级醇,微溶于醚。
  • Sigma Aldrich:109-84-2(sigmaaldrich)
  • 用途一:用作合成呋喃唑酮的中间原料,也可用作植物生长调节剂、聚氨酯和聚丙烯腈的稳定剂、油井腐蚀抑制剂等

系列性分类


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