m-Anisidine 间氨基苯甲醚

CAS 536-90-3 MFCD00007783

化学结构图

536-90-3
SMILES: COc1cccc(N)c1

化学属性

Mol. FormulaC7
Mol. Weight123
Density1.096
Refractive index1.5770 to 1.5840
Flash Point126°C(lit.)
TSCAYes
Boiling Point251
Melting Point-1-1
Solubility微溶于水,溶于乙醇、乙醚、丙酮、苯等多数有机溶剂。
pH:A

别名和识别编码

Chemical Namem-Anisidine
MDL NumberMFCD00007783
CAS Number536-90-3
EC Number208-651-4
Beilstein Registry Number386119
Synonym 3-Methoxyaniline 3-anisidine m-Anisylamine m-anisidine
Merck Number667
PubChem Substance ID10824
Chemical Name Translation间氨基苯甲醚
Reaxys-RN386119
LabNetwork Molecule IDLN00221823
InChIInChI=1S/C7H9NO/c1-9-7-4-2-3-6(8)5-7/h2-5H,8H2,1H3
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分类

  • {SNA} Amines, Building Blocks, C7, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

产品应用

  • 间氨基苯甲醚是药物、染料中间体,高分子材料、铝合金缓蚀剂,重金属离子络合分析试剂,感光材料的还原剂等。

相关文献及参考

  • Merck:14,667
  • Merck:14,667 Beilstein:13(3)932

安全信息

Signal word Warning
GHS Symbol
WGK Germany1
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50/53
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310+P330
  • P301+P312
  • P301+P316
  • P301+P317
  • P302+P352
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P308+P316
  • P309+P311
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P316
  • P317
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P333+P313
  • P337+P313
  • P337+P317
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P361+P364
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSBZ5408000
Packing GroupIII
UN Number 2431
Storage condition Light Sensitive 2-8°C保存 0-10°C 0-10
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H301+H311+H331
  • H302 Harmful if swallowed 吞食有害
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H371 May cause damage to organs 可能导致器官损伤
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 6.1 Xn,N,T+
Hazard Class6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 562 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 562 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 160 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

Restrict 危险品

其他信息

  • 下游产品:3-甲氧基苯磺酰氯 --> 3-甲氧基-N-甲基苯胺 --> 1-(4-甲氧基苯基)哌嗪 --> 1-(3-甲氧基苯基)哌嗪 --> 3-甲氧基苯异氰酸 --> 3-甲氧基苯肼盐酸 --> 对[双(Β-氯乙基)氨基]-邻甲氧基苯甲醛 --> 3-甲氧基-N,N-二(2-羟基乙基)苯胺
  • 毒性分级:中毒
  • 急性毒性:口服-鹌鹑LD50: 562 毫克/公斤;口服-野鸟LD50: 562 毫克/公斤
  • Sigma Aldrich:536-90-3(sigmaaldrich)
  • 用途二:间氨基苯甲醚是药物、染料中间体,高分子材料、铝合金缓蚀剂,重金属离子络合分析试剂,感光材料的还原剂等。
  • Acros Organics:3-氨基茴香醚 m-Anisidine, 99%(536-90-3)
  • 方法一:由间硝基苯酚在羟基上甲基化后经还原而得。
  • 类别:有毒物品
  • 图谱信息:间氨基苯甲醚(536-90-3)红外图谱(IR2) 间氨基苯甲醚(536-90-3)质谱(MS) 间氨基苯甲醚(536-90-3)红外图谱(IR1) 间氨基苯甲醚(536-90-3)核磁图( 1 HNMR) 间氨基苯甲醚(536-90-3)核磁图( 13 CNMR)
  • 间氨基苯甲醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0485 间茴香胺 m-Anisidine 25G 206元 2014/06/02 A0485 间茴香胺 m-Anisidine 500G 1710元 2010/06/21 104820010 间氨基苯甲醚 m-Anisidine 99% 1 LT 2050元
  • 存储注意事项:光敏感
  • 浅黄色油状液体,溶于乙醇、乙醚、苯和稀酸,微溶于水
  • MOL 文件:536-90-3.mol
  • 海关编码:29222200
  • 用途一:用于合成医药、染料、液晶材料中间体
  • 上游原料:甲酚 --> 1,3-二硝基苯 --> 3-硝基苯酚
  • 储运特性:库房通风低温干燥; 与氧化剂、酸类、食品添加剂分开存放
  • TCI Shanghai:3-甲氧基苯胺 m-Anisidine,>;98.0%(GC)(536-90-3)
  • F:8
  • 外观性质:无色或浅黄色油状液体。
  • Alfa Aesar:间茴香胺,98% m-Anisidine, 98%(536-90-3)
  • 灭火剂:二氧化碳、泡沫、砂土、雾状水
  • 可燃性危险特性:遇明火可燃; 燃烧产生有毒氮氧化物烟雾
  • MSDS 信息:间甲氧基苯胺(536-90-3).msds

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