Epinephrine Hydrochloride 盐酸盐肾上腺素

CAS 55-31-2 MFCD00801067

化学结构图

55-31-2
SMILES: Cl.CNC[C@@H](O)C1=CC(O)=C(O)C=C1 |&1:4|

化学属性

Mol. FormulaC9H13NO3.ClH
Mol. Weight219.69
Melting Point157 ºC

别名和识别编码

Chemical NameEpinephrine Hydrochloride
EC Number200-230-3
Synonym Epinephrine chloride {Chemical gelatin-epinephrine (-)-Adrenaline hydrochloride {Chemicalb Adrenalin chloride NCI-C55663 Adrenaline hydrochloride, (-)- l-Adrenaline chloride l-epinephrinechlori 4-(1-hydroxy-2-(methylamino)ethyl)-,hydrochloride,(r)-2-benzenediol (-)-Epinephrine hydrochloride (R)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride adrenalin chloride l-epinephrine hydrochloride l-adrenalinechloride l-Adrenaline hydrochloride l-Epinephrine chloride (-)-adrenalinehydrochlorid l-1-(3,4-dihydroxyphenyl)-2-methylamino-1-ethanolhydrochloride Epinephrine Hydrochl EPINEPHRINE HYDROCHLORIC ACID, USP25 98.0+% Adrenaline hydrochloride l-Epinephrine hydrochloride (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride 盐酸肾上腺素 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, hydrochloride, (R)- (-)-3,4-dihydro nci-c55663 l-1-(3,4-Dihydroxyphenyl)-2-methylamino-1-ethanol hydrochloride Supranephrin solution (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride; (R)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride; Adrenalin chloride l-methyl ADRENALINE CHLORIDE Gelatin-epinephrine supranephrinsolution Adrenaline chloride l-Methylaminoethanolcathechol hydrochloride Epinephrine, hydrochloride (r)-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride (R)-4-[2-(甲氨基)-1-羟基乙基]-1,2-苯二酚盐酸盐 Adrenalin hydrochloride
CAS Number55-31-2
MDL NumberMFCD00801067
Chemical Name Translation盐酸盐肾上腺素
Wiswesser Line NotationQR BQ DYQ1M1 &GH -L
LabNetwork Molecule IDLN01319891
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安全信息

Packing GroupII
Hazard Class6.1(a)
UN Number 3249
RTECSDO3150000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1980 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 87,214,1946

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraduodenal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Phar

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 24,101,1925

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TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 7950 ng/kg
SEX/DURATION            : female 22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   ANREAK Anatomical Record.  (Alan R. Liss, Inc., 41 E. 11th St., New York, NY
   10003)  V.1-    1906/08-  Volume(issue)/page/year: 153,373,1965

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 125 ug/kg
SEX/DURATION            : female 17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - blood and lymphatic
   systems (including spleen and marrow)
REFERENCE :
   BJPCBM British Journal of Pharmacology.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.34-    1968-  Volume(issue)/page/year:
   43,270,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3200 ug/kg
SEX/DURATION            : female 13-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Newborn - stillbirth
REFERENCE :
   CJPPA3 Canadian Journal of Physiology and Pharmacology.  (National Research
   Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6,
   Canada)  V.42-    1964-  Volume(issue)/page/year: 43,473,1965

其他信息

  • 毒性分级:剧毒
  • Sigma Aldrich:55-31-2(sigmaaldrich)
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • 储运特性:库房通风低温干燥; 与食品原料分开存放
  • MOL 文件:55-31-2.mol
  • 急性毒性:口服-小鼠 LD50:24 毫克/公斤;腹腔-小鼠 LD50:50 毫克/公斤
  • MSDS 信息:L-Epinephrine hydrochloride(55-31-2).msds
  • 可燃性危险特性:可燃; 燃烧释放有毒氮氧化物和氯化氢烟雾
  • 类别:有毒物品

系列性分类


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