Dimethylamine hydrochloride 盐酸二甲胺

CAS 506-59-2 MFCD00012477

化学结构图

506-59-2
SMILES: CNC.Cl

化学属性

Mol. FormulaC2H7N.ClH
Mol. Weight81.56
Melting Point171°C
TSCAYes
Solubility3000 G/L (20 ºC)
Density0.64
Appearance 白色叶状晶体。熔点171℃。易溶于水，溶于醇、氯仿，不溶于醚。具潮解性。
Stability易吸潮

别名和识别编码

Chemical NameDimethylamine hydrochloride
Synonym {uni_hamburg} 盐酸二甲胺、盐酸氨基二甲烷 盐酸氨基二甲烷,二甲胺盐酸盐,N-甲基甲胺盐酸盐 Dimethylammonium chloride 二甲胺.盐酸盐;盐酸氨基二甲烷;二甲胺盐酸盐;N-甲基甲胺盐酸盐 Dimethylammonium-chlorid Hydrochloric acid dimethylamine 十二烷基吡啶盐酸盐 hydrochloricaciddimethylamine 二甲胺,盐酸盐 二甲胺盐酸盐 DIMETHYLAMINE HYDROCHLORIDE n-methyl-methanaminhydrochloride dimethylamine hydrochloride Dodecylpyridinehydrochloride METHANAMINE HYDROCHLORIDE dimethylammonium chloride Dimethylamin Hydrochlorid Methanamine,N-methyl-,hydrochloride Dimethylamine HCl 盐酸二甲胺 Dimethylamine, hydrochloride N-甲基甲胺盐酸盐 DIMETHYLAMINE HYDROCHLORIDE Dimethylaminehydrochloride,98+% 二甲基胺氯化氫 Dimethylaminhydrochlorid 氯化氫二甲基胺 二甲胺鹽酸鹽 Methanamine, N-methyl-, hydrochloride 二甲氨基盐酸盐 Dimethylammoniumchlorid N-Methylmethanamine hydrochloride 二甲胺盐酸盐 盐酸氨基二甲烷 DIMETHYLAMINE HCL Dimethyl-ammonium chloride 二甲胺 盐酸盐 Dimethylammonium chioride DimethylAmmoniumChlorideForSynthesis 二甲胺.盐酸盐, 98+% n-methylmethanaminehydrochloride DIMETHYLAMMONIUM CHLORIDE
MDL NumberMFCD00012477
EC Number208-046-5
CAS Number506-59-2
Merck Number14,3228
Beilstein Registry Number3589311
PubChem Substance ID24847723
Chemical Name Translation盐酸二甲胺
Wiswesser Line Notation1M1 &GH
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分类

  • {uni_hamburg} no charge; 2fragments; ionic
  • {SNA} Amine Salts, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

产品应用

  • 二甲胺盐酸盐是有机合成的原料，还用作乙酰化分析的催化剂和镁试剂。

相关文献及参考

  • Merck: 14,3228
  • Short: III/20a
  • Short: IV/1a
  • Short: III/5a
  • Merck: 14,3228 Beilstein: 4,IV,132

安全信息

RTECSIQ0220000
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Storage condition 密封干燥保存。 Hygroscopic
GHS Symbol
WGK Germany1
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard Codes Xn
Restrict 监控化学品 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 gm/kg/Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - bronchiogenic carcinoma
   Liver - tumors
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 44(8),15,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 32(6),12,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 112,36,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 32(6),12,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1070 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 32(6),12,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3825 mg/kg
SEX/DURATION            : female 1-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 32,319,1991

其他信息

  • 方法一:由二甲胺与盐酸成盐而得。将盐酸缓缓滴入二甲胺中，30%的盐酸用量约为40%二甲胺的1.1倍，滴入速度以温度不超过15℃，pH=7-8为限。反应结束后，加活性炭脱色，过滤，滤液用盐酸调节至pH=3-4，减压蒸水至尽，得二甲胺盐酸盐。
  • MSDS 信息:Dimethylammonium chloride(506-59-2).msds
  • 上游原料:二甲胺
  • Alfa Aesar:二甲胺.盐酸盐,98+% Dimethylamine hydrochloride, 98+%(506-59-2)
  • 用途二:用作制药的原料
  • 海关编码:29211190
  • 用途三:二甲胺盐酸盐是有机合成的原料，还用作乙酰化分析的催化剂和镁试剂。
  • 图谱信息:盐酸二甲胺(506-59-2)红外图谱(IR1) 盐酸二甲胺(506-59-2)核磁图( 13 CNMR) 盐酸二甲胺(506-59-2)红外图谱(IR2) 盐酸二甲胺(506-59-2)质谱(MS) 盐酸二甲胺(506-59-2)核磁图( 1 HNMR)
  • 用途一:乙酰化分析时用作催化剂，也用于有机合成和二甲胺水溶液的制备
  • 下游产品:利尿酸 --> 萎蔫酸 --> 5-丁基吡啶-2-甲腈 --> (3S)-(-)-3-(二甲氨基)吡咯烷 --> 恩丹西酮 --> 2-氯-N,N-二甲基乙酰胺 --> (3R)-(+)-3-二甲氨基吡咯烷 --> 二甲基氨基氯化氢 --> 4-二甲氨基哌啶 --> 二甲胺基磺酰氯 --> N-亚硝基二甲胺
  • 敏感性:Hygroscopic
  • MOL 文件:506-59-2.mol
  • Sigma Aldrich:506-59-2(sigmaaldrich)
  • 有挥发性。易潮解。易溶于水，溶于乙醇和氯仿，几乎不溶于乙醚。有刺激性。
  • Acros Organics:二甲氨基盐酸盐 Dimethylamine hydrochloride, 99%(506-59-2)
  • F:3-9
  • 盐酸二甲胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30067025 二甲胺盐酸盐(XZ) 50g 10元 2011/08/23 30067026 二甲胺盐酸盐(XZ) 100g 17.6元 2010/06/21 155275000 盐酸二甲胺 Dimethylamine hydrochloride 99% 500 GR 442元

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amine Salts - Nitrogen Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amidates/Imidates