2-(Bis(2-Hydroxyethyl)Amino)-Ethanesulfonicacid N,N-双(2-羟乙基)-2-氨基乙磺酸

CAS 10191-18-1 MFCD00007533

化学结构图

10191-18-1
SMILES: OS(=O)(=O)CCN(CCO)CCO

化学属性

Mol. FormulaC6H15NO5S
Mol. Weight213
Melting Point152-154
SolubilitySoluble in water
TSCAYes
Density1.437

别名和识别编码

Chemical Name2-(Bis(2-Hydroxyethyl)Amino)-Ethanesulfonicacid
Synonym BES BES (buffering agent) N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid N,N-双(2-羟乙基)-2-氨基乙磺酸 Taurine, N,N-bis(2-hydroxyethyl)-
PubChem Substance ID87563874
EC Number233-465-5
Beilstein Registry Number1781572
MDL NumberMFCD00007533
CAS Number10191-18-1
Reaxys-RN1781572
Chemical Name TranslationN,N-双(2-羟乙基)-2-氨基乙磺酸
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分类

  • {SNA} BioPerformance Certified Buffers, Buffers A to Z, Good’s Buffers, 生化试剂, 生物缓冲液
  • {SNA}
  • {SNA} BioReagent Buffers, Biochemicals and Reagents, Biological Buffers, Buffers A to Z,
  • {SNA} BioReagent Buffers, Biological Buffers, Buffers A to Z, Good’s Buffers
  • {SA} Biological Buffers, Buffers A to Z,

产品应用

  • 生物缓冲剂。
  • A zwitterionic buffer that is used in research in the pH range of 6.15 - 8.35

相关文献及参考

  • Biological buffer, pKa 7.15 at 20xC: Biochemistry, 5, 467 (1966).
  • Beilstein: 4,IV,3290

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSKI7363500
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
Storage condition 室温
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982

其他信息

  • useful pH range 6.4 - 7.8
  • BES, Free Acid is a zwitterionic buffer that is used in biochemistry and molecular biology research in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. A protocol has been reported for the use of BES buffered saline in the calcium phosphate mediated transfection of eukaryotic cells with plasmid DNA.

系列性分类


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