1-Bromo-2-Methylpropane 1-溴-2-甲基丙烷

CAS 78-77-3 MFCD00000217

化学结构图

78-77-3
SMILES: CC(C)CBr

化学属性

Mol. FormulaC4H9Br
Mol. Weight137
Density1.26
Refractive index1.4340 to 1.4390
Boiling Point92°C
Flash Point18°C(lit.)
SolubilitySlightly soluble in water. Miscible with alcohol, ether
TSCAYes
Melting Point-118°
Stability对光敏感

别名和识别编码

Synonym bromoisobutane Isobutylbromid 1-Bromo-2-methylpropane, 98+% Isobutyl bromide 2-Methylpropylbromid 1-溴代异丁烷 Isobutylbromide,97% 溴代异丁烷 1-溴异丁烷 溴化异丁基 1-溴-2-甲基丙烷,1-溴-2甲基丙烷,异丁基溴,溴化异丁基,1-溴代异丁烷 1-溴-2甲基丙烷 iso-C4H9Br Propane,1-bromo-2-methyl- Bromoisobutane isobutyl bromide ISOBUTYL BROMIDE ISOBUTYL BROMIDE / 1-BROMO-2-METHYLPROPANE 1-Brom-2-methylpropan 1-Bromo-iso-butame 1-bromo-2-methyl-propane iso-Butyl bromide i-Butyl bromide 1-bromo-2-methyl-propan 1-溴-2-甲基丙烷, 98+% 异丁基溴
CAS Number78-77-3
EC Number201-141-2
Beilstein Registry Number1,126
MDL NumberMFCD00000217
PubChem Substance ID87563624
Merck Number14,5135
Reaxys-RN1730915
Chemical Name Translation1-溴-2-甲基丙烷
Wiswesser Line NotationE1Y1&1
LabNetwork Molecule IDLN00224680
Chemical Name1-Bromo-2-Methylpropane
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分类

  • {SNA} Alkyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks
  • {uni_hamburg} no charge; 1fragment

产品应用

  • 溶剂、有机合成和医药中间体。

相关文献及参考

  • Merck: 14,5135 Beilstein:1,126
  • Merck: 14,5135
  • Short: II/24B
  • Short: II/24C

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S37 Wear suitable gloves 戴适当手套;
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用(指明具体的消防器材种类,如果用水增加危险,注明“禁止用水”
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R37 Irritating to respiratory system 刺激呼吸道
  • R11 Highly flammable 非常易燃
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P305+P351+P338
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTX4140000
Packing GroupII
UN Number 2342 UN 2342 3/PG 2
Hazard Codes F;Xi
Storage condition Flammables area 避光保存
Hazard Class3
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3000 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,1411,1975

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 50500 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 18(4),55,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1660 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 20(12),52,1976

Restrict 危险品

其他信息

  • 毒性分级:中毒
  • 方法一:将异丁醇冷至-10℃,慢慢滴加三溴化磷,保持反应液在0℃以下。滴加完毕,搅拌下自然升温至室温,放置过夜,用减压蒸馏提纯得到1-溴-2-甲基丙烷。
  • Acros Organics:1-溴-2-甲基丙烷 1-Bromo-2-methylpropane, 98+%(78-77-3)
  • TCI Shanghai:1-溴-2-甲基丙烷 1-Bromo-2-methylpropane,>;97.0%(GC)(78-77-3)
  • MSDS 信息:1-溴-2-甲基丙烷(78-77-3).msds
  • 海关编码:29033036
  • 灭火剂:雾状水、泡沫、砂土、二氧化碳、1211灭火剂
  • 用途二:用作溶剂,也用于有机合成
  • 类别:易燃液体
  • 上游原料:异丁醇
  • 图谱信息:溴代异丁烷(78-77-3)红外图谱(IR2) 溴代异丁烷(78-77-3)核磁图( 1 HNMR) 溴代异丁烷(78-77-3)红外图谱(IR1) 溴代异丁烷(78-77-3)核磁图( 13 CNMR) 溴代异丁烷(78-77-3)质谱(MS)
  • 急性毒性:腹注- 小鼠 LD50: 1660 毫克/ 公斤
  • 用途三:溶剂、有机合成和医药中间体。
  • 易燃。微溶于水,溶解度:0.51 g/L (18°C),溶于乙醇、乙醚等大多数有机溶剂。
  • 溴代异丁烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80024526 溴代异丁烷 100ml 80元 2011/04/16 B0616 1-溴-2-甲基丙烷 1-Bromo-2-methylpropane 500G 665元 2011/04/16 B0616 1-溴-2-甲基丙烷 1-Bromo-2-methylpropane 25G 142元
  • Sigma Aldrich:78-77-3(sigmaaldrich)
  • Alfa Aesar:1-溴-2-甲基丙烷,98+% 1-Bromo-2-methylpropane, 98+%(78-77-3)
  • 储运特性:库房通风低温干燥; 轻装轻卸、与氧化剂和酸类分开存放
  • F:8
  • 可燃性危险特性:明火、受热、氧化剂可燃; 遇酸、受热放出含溴化物有毒气体
  • MOL 文件:78-77-3.mol
  • 外观性质:无色液体。
  • 下游产品:西布曲明 --> 异丁胺 --> 异丁硫醇
  • 用途一:用作有机合成中间体

系列性分类


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